Patents by Inventor Jack Gorski

Jack Gorski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6194147
    Abstract: A method for HLA typing by amplification of a sample followed by sequence-specific oligonucleotide hybridization with a labelled oligonucleotide probe provides for both positive and negative controls. Control sequences representing known allelic polymorphisms at the locus in question are subjected to the labelled probe along with the sample. This method reduces errors and improves the chance of obtaining a successful tissue match, as is vital in the case of tissue transplants, particularly bone marrow transplants. Probes and PCR primers useful in HLA-DR typing are also provided.
    Type: Grant
    Filed: December 30, 1997
    Date of Patent: February 27, 2001
    Assignee: The Blood Center Research Foundation, Inc.
    Inventors: Lee Ann Baxter-Lowe, Jack A. Gorski
  • Patent number: 5837447
    Abstract: An approach to monitoring immune responses relies on determining the range of sizes of amplified DNAs which code for the CDR3 regions of Ig or TcR molecules of one or more classes or families. Typically the relative quantity of DNAs corresponding to different CDR3 regions of the Ig or TcR molecules of a class is also determined. The progress of an immune response is followed by making these determinations at different times.
    Type: Grant
    Filed: April 19, 1994
    Date of Patent: November 17, 1998
    Assignee: Blood Center Research Foundation, Inc., The
    Inventor: Jack Gorski
  • Patent number: 5702885
    Abstract: A method for HLA typing by amplification of a sample followed by sequence-specific oligonucleotide hybridization with a labelled oligonucleotide probe provides for both positive and negative controls. Control sequences representing known allelic polymorphisms at the locus in question are subjected to the labelled probe along with the sample. This method reduces errors and improves the chance of obtaining a successful tissue match, as is vital in the case of tissue transplants, particularly bone marrow transplants. Probes and PCR primers useful in HLA-DR typing are also provided.
    Type: Grant
    Filed: April 8, 1993
    Date of Patent: December 30, 1997
    Assignee: The Blood Center Research Foundation, Inc.
    Inventors: Lee Ann Baxter-Lowe, Jack A. Gorski
  • Patent number: 5468611
    Abstract: A method for HLA typing by amplification of a sample followed by sequence-specific oligonucleotide hybridization with a labelled oligonucleotide probe provides for both positive and negative controls. Control sequences representing known allelic polymorphisms at the locus in question are subjected to the labelled probe along with the sample. This method reduces errors and improves the chance of obtaining a successful tissue match, as is vital in the case of tissue transplants, particularly bone marrow transplants. Probes and PCR primers useful in HLA-DR typing are also provided.
    Type: Grant
    Filed: April 8, 1993
    Date of Patent: November 21, 1995
    Assignee: The Blood Center Research Foundation, Inc.
    Inventors: Lee A. Baxter-Lowe, Jack A. Gorski
  • Patent number: 5010011
    Abstract: Portions of the genetic sequence coding for bovine placental lactogen are isolated and a cDNA variant of a bovine placental lactogen gene is then formed and isolated. Upon cloning of the cDNA gene sequence and culturing of a resulting host, large quantities of bovine placental lactogen can be produced.
    Type: Grant
    Filed: April 21, 1988
    Date of Patent: April 23, 1991
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Linda A. Schuler, Jack Gorski, Walter L. Hurley, Robert D. Bremel, Fritz M. Rottman
  • Patent number: 4767711
    Abstract: Portions of the genetic sequence coding for bovine placental lactogen are isolated and a cDNA variant of the bovine placental lactogen gene is then formed and isolated. Upon cloning of the cDNA gene sequence and culturing of a resulting hose, large quantities of bovine placental lactogen can be produced.
    Type: Grant
    Filed: March 28, 1985
    Date of Patent: August 30, 1988
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Linda A. Schuler, Jack Gorski, Walter L. Hurley, Robert D. Bremel, Fritz M. Rottman