Patents by Inventor Jack Greiner

Jack Greiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topical Phospholipid Formulations and Methods for Preparing the Same
    Publication number: 20200297591
    Abstract: A topical phospholipid formulation is provided that includes a phospholipid component. The phospholipid component is anionic and exhibits a net negative charge at physiologic pH. Methods of preparing such a formulation are also provided.
    Type: Application
    Filed: March 12, 2020
    Publication date: September 24, 2020
    Inventors: Thomas GLONEK, Jack GREINER, Donald KORB, Hridaya BHARGAVA
  • Topical Phospholipid Formulations and Methods for Preparing the Same
    Publication number: 20190282465
    Abstract: A topical phospholipid formulation is provided that includes a phospholipid component. The phospholipid component is anionic and exhibits a net negative charge at physiologic pH. Methods of preparing such a formulation are also provided.
    Type: Application
    Filed: March 18, 2019
    Publication date: September 19, 2019
    Inventors: Thomas GLONEK, Jack GREINER, Donald KORB, Hridaya BHARGAVA
  • Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives
    Patent number: 9249089
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: February 2, 2016
    Assignee: REATA PHARMACEUTICALS, INC.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives
    Patent number: 8394967
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: March 12, 2013
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Antioxidant inflammation modulators: novel derivatives of oleanolic acid
    Patent number: 8338618
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: December 25, 2012
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID
    Publication number: 20120238767
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Application
    Filed: November 11, 2011
    Publication date: September 20, 2012
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • Antioxidant inflammation modulators: novel derivatives of oleanolic acid
    Patent number: 8071632
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: December 6, 2011
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • ANTIOXIDANT INFLAMMATION MODULATORS: C-17 HOMOLOGATED OLEANOLIC ACID DERIVATIVES
    Publication number: 20110245206
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: February 23, 2011
    Publication date: October 6, 2011
    Inventors: XIN JIANG, XIAOFENG LIU, JACK GREINER, STEPHEN S. SZUCS, MELEAN VISNICK
  • Antioxidant inflammation modulators: C-17 homologated oleanolic acid derivatives
    Patent number: 7943778
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: May 17, 2011
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID
    Publication number: 20100048911
    Abstract: Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.
    Type: Application
    Filed: April 20, 2009
    Publication date: February 25, 2010
    Inventors: Xin Jiang, Jack Greiner, Lester L. Maravetz, Stephen S. Szucs, Melean Visnick
  • ANTIOXIDANT INFLAMMATION MODULATORS: C-17 HOMOLOGATED OLEANOLIC ACID DERIVATIVES
    Publication number: 20100041904
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Application
    Filed: April 20, 2009
    Publication date: February 18, 2010
    Inventors: Xin Jiang, Xiaofeng Liu, Jack Greiner, Stephen S. Szucs, Melean Visnick
  • Dry eye treatment solution
    Patent number: 5278151
    Abstract: A method and composition for reducing evaporation of an aqueous layer from the surface of the eye. The method comprises applying an admixture of a charged phospholipid and a non-polar oil over the eye, preferably in the form of a finely divided oil in water emulsion.
    Type: Grant
    Filed: June 9, 1992
    Date of Patent: January 11, 1994
    Assignee: Ocular Research of Boston, Inc.
    Inventors: Donald R. Korb, Thomas Glonek, Jack Greiner