Abstract: An apparatus for controlling fluid volumes, comprising: a motor; a camshaft connected to the motor at a rotational axis of the camshaft; at least one cam disposed on a circumference of the camshaft; a pin frame; at least one pin disposed in the pin frame and operatively associated with the at least one cam, wherein rotation of the camshaft by the motor contacts the at least one cam to the at least one pin, driving the at least one pin in a first direction.

Abstract: Various embodiments of the present disclosure disclose methods and systems for heat exchange in an opto-fluidic instrument. The opto-fluidic instrument includes a sample interface module (SIM), an illumination module, a camera module, and a reagent deck. A coolant from a coolant reservoir is directed into one or more of the modules so that heat exchange occurs at each module with the coolant. The heated coolant from the one or more modules flows to a radiator for cooling, for example, with fans flowing ambient air over the radiator, before the cooled coolant is returned to the coolant reservoir for subsequent use in cooling the modules.

Abstract: The present disclosure relates to systems and methods for thermal management of well plates. In various embodiments, an apparatus for performing thermal management includes a thermal transfer block configured to receive a well plate having a plurality of wells, wherein the thermal transfer block comprises a base and a plurality of protrusions arranged on a first side of the base in a configuration such that each of the plurality of wells is received between a set of adjacent protrusions, and wherein each protrusion of the set of adjacent protrusions has a surface that substantially matches a portion of an outer surface of each well that is received between the set of adjacent protrusions; and a cooling block disposed in contact with a second side of the base of the thermal transfer block, wherein the cooling block comprises a heat sink having a plurality of fins immersed in a fluid for cooling.

Abstract: An apparatus for controlling fluid volumes, comprising: a motor; a camshaft connected to the motor at a rotational axis of the camshaft; at least one cam disposed on a circumference of the camshaft; a pin frame; at least one pin disposed in the pin frame and operatively associated with the at least one cam, wherein rotation of the camshaft by the motor contacts the at least one cam to the at least one pin, driving the at least one pin in a first direction.