Abstract: Provided herein are methods for cell therapy by modifying transfused cells to express an inducible caspase 9 protein, so that the cells may be selectively killed if the patient experiences dangerous side effects. Provided also within relates in part to methods for preventing or treating Graft versus Host Disease by modifying T cells before administration to a patient, so that they may be selectively killed if GvHD develops in the patient.

Abstract: Provided herein are methods for cell therapy by modifying transfused cells to express an inducible caspase 9 protein, so that the cells may be selectively killed if the patient experiences dangerous side effects. Provided also within relates in part to methods for preventing or treating Graft versus Host Disease by modifying T cells before administration to a patient, so that they may be selectively killed if GvHD develops in the patient.

Abstract: An insect exterminating device which is characterized in a first embodiment by a handle having a handle base attached to a downwardly-extending probe frame fitted with a bracket and a spring for receiving an aerosol or pressurized fluid canister containing an insect treatment fluid. A probe projects from the probe frame and a spring-loaded activator button is provided on the handle base for activating the pressurized fluid canister valve to dispense the treatment fluid from the canister, through passages provided in the activator button, the handle base, the probe frame and the probe, into an insect bed. In a preferred embodiment the bracket is adjustable for accommodating pressurized fluid containers of various length. In a second embodiment the fluid canister is seated on a spring in a round frame and the treatment fluid is dispersed from the canister through a tube to the probe by pressing a spring-loaded activator button.