Patents by Inventor Jack JHAMANDAS

Jack JHAMANDAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for the treatment of Alzheimer's disease
    Patent number: 11939302
    Abstract: The present disclosure provides compounds that are amylin receptor antagonist compounds, compositions that include the subject compounds, methods for preparing and using the amylin receptor antagonists, and compositions containing the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease. Aspects of the present disclosure include a method of inhibiting activity of an amylin receptor by administering to a subject in need thereof a therapeutically effective amount of an amylin receptor antagonist.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: March 26, 2024
    Assignee: The Governors of the University of Alberta
    Inventors: James A. Nieman, Jack Jhamandas, Bing Bai, Alexandr Belovodskiy, Wen Fu, Mostofa Hena, Michael Houghton, Appan Srinivas Kandadai, Ryoichi Kimura, Kamlesh Kumar Sahu, D. Lorne Tyrrell
  • Non-Peptidic Heterocycle-Containing Compounds for the Treatment of Alzheimer?s Disease
    Publication number: 20220226335
    Abstract: The present disclosure provides non-peptidic heterocycle-containing amylin receptor antagonist compounds, compositions that include the subject compounds, methods for preparing and using the amylin receptor antagonists, and compositions containing the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease. Aspects of the present disclosure include a method of inhibiting activity of an amylin receptor by administering to a subject in need thereof a therapeutically effective amount of an amylin receptor antagonist.
    Type: Application
    Filed: April 23, 2020
    Publication date: July 21, 2022
    Inventors: Jack Jhamandas, Wen Fu, Ryoichi Kimura, D. Lorne Tyrrell, Ana Clementin, Kamlesh Sahu, Alexandr Belovodskiy, Mostofa Hena, Bing Bai, Appan Srinivas Kandadai, James A. Nieman, Michael Houghton
  • Compounds for the Treatment of Alzheimer's Disease
    Publication number: 20220119356
    Abstract: The present disclosure provides compounds that are amylin receptor antagonist compounds, compositions that include the subject compounds, methods for preparing and using the amylin receptor antagonists, and compositions containing the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease. Aspects of the present disclosure include a method of inhibiting activity of an amylin receptor by administering to a subject in need thereof a therapeutically effective amount of an amylin receptor antagonist.
    Type: Application
    Filed: October 19, 2021
    Publication date: April 21, 2022
    Inventors: James A. Nieman, Jack Jhamandas, Bing Bai, Alexandr Belovodskiy, Wen Fu, Mostofa Hena, Michael Houghton, Appan Srinivas Kandadai, Ryoichi Kimura, Kamlesh Kumar Sahu, D. Lorne Tyrrell
  • Brain penetrant amylin receptor based peptides for Alzheimer's disease
    Patent number: 10766940
    Abstract: Amylin receptor antagonists capable of binding to the amylin receptor and inhibiting activity of amylin or amyloid-beta protein are provided. The amylin receptor antagonists can be administered in the form of pharmaceutical compositions or the like. Methods for preparing and using the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease are also provided.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: September 8, 2020
    Assignee: The Governors of the University of Alberta
    Inventors: Jack Jhamandas, Rania Soudy, Kamaljit Kaur, Wen Fu, David MacTavish, Aarti Patel
  • BRAIN PENETRANT AMYLIN RECEPTOR BASED PEPTIDES FOR ALZHEIMER'S DISEASE
    Publication number: 20180134763
    Abstract: Amylin receptor antagonists capable of binding to the amylin receptor and inhibiting activity of amylin or amyloid-beta protein are provided. The amylin receptor antagonists can be administered in the form of pharmaceutical compositions or the like. Methods for preparing and using the amylin receptor antagonists for treating, preventing, or ameliorating Alzheimer's disease are also provided.
    Type: Application
    Filed: September 15, 2017
    Publication date: May 17, 2018
    Inventors: Jack JHAMANDAS, Rania SOUDY, Kamaljit KAUR, Wen FU, David MacTAVISH, Aarti PATEL