Patents by Inventor Jack Kessler

Jack Kessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10962533
    Abstract: Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced Raman spectroscopy (SERS)-active nanoparticles, each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample. Further, agitating magnetic capture particles also having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest can be used to capture the microorganism-indicator particle complex and concentrate the complex in a localized area of an assay vessel for subsequent detection and identification. The complex can be dispersed, pelleted, and redispersed so that the culture sample can be retested a number of times during incubation so as to allow for real-time monitoring of the culture sample.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: March 30, 2021
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Kristin Weidemaier, Erin Gooch Carruthers, Adam C. Curry, Melody M. H. Kuroda, Ammon David Lentz, Michael Justin Lizzi, Eric A. Fallows, Donald E. Gorelick, Jack Kessler, Spencer Lovette, Jeffrey S. Ojala, Mark A. Talmer
  • Publication number: 20190381093
    Abstract: This invention relates generally to an emollient topical composition of matter that contains molecular iodine with a reduced effective vapor pressure. In specific embodiments, the composition reduces the loss of molecular iodine to the atmosphere under storage conditions after application to mammalian tissue.
    Type: Application
    Filed: July 19, 2017
    Publication date: December 19, 2019
    Inventors: Jack KESSLER, David C. LITZINGER, Christopher RHODES, Andrew M. CERRO
  • Publication number: 20190105344
    Abstract: Oral pharmaceutical compositions comprising iodide, iodate and. arachidonic acid in the presence of other pharmaceutical excipients and methods for preparing and using these compositions.
    Type: Application
    Filed: September 15, 2017
    Publication date: April 11, 2019
    Inventor: Jack KESSLER
  • Publication number: 20180360048
    Abstract: The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (I2) and an acceptable source of iodate (IO3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering pH in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g. antiviral, antibacterial, antifungal, antispore etc.
    Type: Application
    Filed: August 23, 2018
    Publication date: December 20, 2018
    Inventors: Rodger Elliot Kolsky, Herbert Moskowitz, Jack Kessler
  • Publication number: 20180296594
    Abstract: The invention is a solid oral dosage form that is designed to deliver a supraphysiological dose of molecular iodine of 3 to 60 mg per day. The solid oral dosage form is designed to have a low risk of thyroid related adverse clinical events for patients with deficiencies of certain minerals. The solid oral dosage form includes a source of iodine, a reactive agent, and calcium or iron. The solid oral dosage form may include one or more of selenium, vitamin A, vitamin D, zinc, gamma-linolenic acid, vitamin B1, and magnesium. The solid dosage form may further comprise an enteric coating that coats ingredients that are absorbed predominantly from the intestines, such as vitamin A and D, and does not coat the source of iodine and the reactive agent.
    Type: Application
    Filed: June 22, 2018
    Publication date: October 18, 2018
    Inventors: Jack Kessler, Robert Kehl Sink
  • Patent number: 10092006
    Abstract: The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (I2) and an acceptable source of iodate (IO3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering pH in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g. antiviral, antibacterial, antifungal, antispore etc.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: October 9, 2018
    Assignee: ioTECH INTERNATIONAL
    Inventors: Rodger Elliot Kolsky, Herbert Moskowitz, Jack Kessler
  • Patent number: 10034899
    Abstract: The invention is a solid oral dosage form that is designed to deliver a supraphysiological dose of molecular iodine of 3 to 60 mg per day. The solid oral dosage form is designed to have a low risk of thyroid related adverse clinical events for patients with deficiencies of certain minerals. The solid oral dosage form includes a source of iodine, a reactive agent, and calcium or iron. The solid oral dosage form may include one or more of selenium, vitamin A, vitamin D, zinc, gamma-linolenic acid, vitamin B1, and magnesium. The solid dosage form may further comprise an enteric coating that coats ingredients that are absorbed predominantly from the intestines, such as vitamin A and D, and does not coat the source of iodine and the reactive agent.
    Type: Grant
    Filed: November 22, 2014
    Date of Patent: July 31, 2018
    Assignee: BioPharmX, Inc.
    Inventors: Jack Kessler, Robert Kehl Sink
  • Publication number: 20180136204
    Abstract: Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced Raman spectroscopy (SERS)-active nanoparticles, each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample. Further, agitating magnetic capture particles also having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest can be used to capture the microorganism-indicator particle complex and concentrate the complex in a localized area of an assay vessel for subsequent detection and identification. The complex can be dispersed, pelleted, and redispersed so that the culture sample can be retested a number of times during incubation so as to allow for real-time monitoring of the culture sample.
    Type: Application
    Filed: November 27, 2017
    Publication date: May 17, 2018
    Applicant: BECTON DICKINSON AND COMPANY
    Inventors: Kristin Weidemaier, Robert L. Campbell, Erin Gooch Carruthers, Adam Craig Curry, Kevin G. Dolan, Andrea Liebmann-Vinson, Wendy Dale Woodley, Melody M.H. Kuroda, Ammon David Lentz, Dwight Livingston, Michael Justin Lizzi, Artis R. Lockhart, Ernie Ritchey, Eric A. Fallows, Donald E. Gorelick, Jack Kessler, Spencer Lovette, Jeffrey S. Ojala, Mark A. Talmer, Miroslaw Bartkowiak, Scott N. Danhof, Gregory S. Kramer, Thomas D. Haubert, Michael L. Marshall, James A. Prescott, Randy J. Somerville, M. Scott Ulrich, David S. Sebba
  • Publication number: 20170335408
    Abstract: The instant disclosure provides methods of multi-assay processing and multi-assay analysis. Such multi-assay processing and analysis pertain to automated detection of target nucleic acids, e.g., as performed in the clinical setting for diagnostic purposes. Also provided are common assay timing protocols derived from a variety of individual nucleic acid amplification and analysis protocols and modified to prevent resource contention. The instant disclosure also provides systems and devices for practicing the methods as described herein.
    Type: Application
    Filed: March 15, 2017
    Publication date: November 23, 2017
    Inventors: Frank Pawlowski, Joseph P. Skinner, Jack Kessler, Sonal Sadaria Nana
  • Publication number: 20170208814
    Abstract: The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (I2) and an acceptable source of iodate (IO3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering pH in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g. antiviral, antibacterial, antifungal, antispore etc.
    Type: Application
    Filed: March 26, 2015
    Publication date: July 27, 2017
    Inventors: Rodger Elliot KOLSKY, Herbert MOSKOWITZ, Jack KESSLER
  • Publication number: 20160054307
    Abstract: Assay devices, assay detection systems, and methods comprising same for analytical tests, medical assays, diagnostic tests, medical diagnosis, risk assessment, or quality control purposes are provided. These devices, systems, and methods are designed to be employed at the point of care, such as in emergency rooms, operating rooms, hospital laboratories and other clinical laboratories, doctor's offices, in the field, or in any situation in which a rapid and accurate result is desired. The systems and methods process samples, such as clinical, biological, or blood sample, and read data from colorimetric based biochemical assays to provide an indication of the presence or absence of a bacterial, fungal, or viral contaminants therein. The assay devices include an optical reader apparatus and barcode scanner for reading and matching the test results to identification information provided by the barcodes to facilitate ease of tracking compliant and noncompliant samples.
    Type: Application
    Filed: March 23, 2015
    Publication date: February 25, 2016
    Inventors: Richard A. Pinkowitz, Michael J. Ockham, Gregory V. Williams, Neil X. Krueger, Andrew Han, Lynda S. Mungo, James L. Dowling, Jason S. Minahan, Jack Kessler, Gary Chevalier, Roger T. Lacroix
  • Publication number: 20150185208
    Abstract: Assay devices, assay detection systems, and methods comprising same for analytical tests, medical assays, diagnostic tests, medical diagnosis, risk assessment, or quality control purposes are provided. These devices, systems, and methods are designed to be employed at the point of care, such as in emergency rooms, operating rooms, hospital laboratories and other clinical laboratories, doctor's offices, in the field, or in any situation in which a rapid and accurate result is desired. The systems and methods process samples, such as clinical, biological, or blood sample, and read data from colorimetric based biochemical assays to provide an indication of the presence or absence of a bacterial, fungal, or viral contaminants therein. The assay devices include an optical reader apparatus and barcode scanner for reading and matching the test results to identification information provided by the barcodes to facilitate ease of tracking compliant and noncompliant samples.
    Type: Application
    Filed: October 14, 2014
    Publication date: July 2, 2015
    Inventors: Richard A. Pinkowitz, Michael J. Ockham, Gregory V. Williams, Neil X. Krueger, Andrew Han, Lynda S. Mungo, James L. Dowling, Jason S. Minahan, Jack Kessler, Gary Chevalier, Roger T. Lacroix
  • Publication number: 20150147400
    Abstract: The invention is a solid oral dosage form that is designed to deliver a supraphysiological dose of molecular iodine of 3 to 60 mg per day. The solid oral dosage form is designed to have a low risk of thyroid related adverse clinical events for patients with deficiencies of certain minerals. The solid oral dosage form includes a source of iodine, a reactive agent, and calcium or iron. The solid oral dosage form may include one or more of selenium, vitamin A, vitamin D, zinc, gamma-linolenic acid, vitamin B1, and magnesium. The solid dosage form may further comprise an enteric coating that coats ingredients that are absorbed predominantly from the intestines, such as vitamin A and D, and does not coat the source of iodine and the reactive agent.
    Type: Application
    Filed: November 22, 2014
    Publication date: May 28, 2015
    Applicant: BioPharmX, Inc
    Inventors: Jack Kessler, Robert Kehl Sink
  • Publication number: 20150118688
    Abstract: Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced Raman spectroscopy (SERS)-active nanoparticles, each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample. Further, agitating magnetic capture particles also having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest can be used to capture the microorganism-indicator particle complex and concentrate the complex in a localized area of an assay vessel for subsequent detection and identification. The complex can be dispersed, pelleted, and redispersed so that the culture sample can be retested a number of times during incubation so as to allow for real-time monitoring of the culture sample.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 30, 2015
    Inventors: Kristin Weidemaier, Robert L. Campbell, Erin Gooch Carruthers, Adam C. Curry, Kevin G. Dolan, Andrea Liebmann-Vinson, Wendy Dale Woodley, Melody M.H. Kuroda, Ammon David Lentz, Dwight Livingston, Michael Justin Lizzi, Artis R. Lockhart, Ernie Ritchey, Eric A. Fallows, Donald E. Gorelick, Jack Kessler, Spencer Lovette, Jeffrey S. Ojala, Mark A. Talmer, Miroslaw Bartkowiak, Scott N. Danhof, Gregory S. Kramer, Thomas D. Haubert, Michael L. Marshall, James A. Prescott, Randy J. Somerville, M. Scott Ulrich, David S. Sebba
  • Patent number: 8533888
    Abstract: A shoe cleaning doormat device is provided for cleaning and disinfecting the soles of shoes and feet prior to a user's entry into a dwelling or building. The device is a doormat having a cleaning assembly having a disinfecting cleaning material surface and drying portions. Both portions are housed within a mat frame and exposed to a user through cutouts in the mat's upper surface. A disposable roll of moist, disinfecting wipe material provides the cleaning and disinfecting surface. An advancing button is operatively connected to the roll so that a user may obtain an unused portion of the roll by depressing the button. After shoes or feet are cleaned, they can be dried by rubbing on the drying portions of the device, which comprise a removable, moisture-absorbing material.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: September 17, 2013
    Inventor: Jack Kessler
  • Publication number: 20120042460
    Abstract: A shoe cleaning doormat device is provided for cleaning and disinfecting the soles of shoes and feet prior to a user's entry into a dwelling or building. The device is a doormat having a cleaning assembly having a disinfecting cleaning material surface and drying portions. Both portions are housed within a mat frame and exposed to a user through cutouts in the mat's upper surface. A disposable roll of moist, disinfecting wipe material provides the cleaning and disinfecting surface. An advancing button is operatively connected to the roll so that a user may obtain an unused portion of the roll by depressing the button. After shoes or feet are cleaned, they can be dried by rubbing on the drying portions of the device, which comprise a removable, moisture-absorbing material.
    Type: Application
    Filed: August 19, 2011
    Publication date: February 23, 2012
    Inventor: Jack Kessler
  • Publication number: 20090017139
    Abstract: A method for therapeutically treating medical conditions requiring chronic therapy such as fibrocystic breast disease, endometriosis, ovarian cysts, uterine fibroids and including the treatment of women considered to be at risk to breast and/or ovarian cancer without causing an overt thyroid disease by first administering to a patient a daily loading dose of molecular iodine (I2) for a time period not to exceed six months and preferably 2 to 4 months at a concentration level sufficient to remediate symptoms associated with the medical condition followed by daily dosing with a maintenance dose of I2 after treatment of the loading dose is completed with the concentration of the maintenance dose being substantially less than the concentration of the loading dose.
    Type: Application
    Filed: July 12, 2007
    Publication date: January 15, 2009
    Inventor: Jack Kessler
  • Publication number: 20030026852
    Abstract: This invention describes a non-aqueous oral composition of molecular iodine in a stabilized hydrophobic environment containing a hydrophobe or combination of hydrophobes for treating different disease states.
    Type: Application
    Filed: March 27, 2001
    Publication date: February 6, 2003
    Applicant: SYMBOLLON CORPORATION
    Inventors: Yongjun Duan, Jack Kessler
  • Patent number: 6432426
    Abstract: Non-staining topical iodine disinfecting compositions having the ability to inactivate pathogens associated with skin infections or diseases. based upon the presence of molecular iodine in a concentration above at least 15 ppm. Any other iodine species selected from the group consisting of complexed iodine and triiodide may be present with the total of such other iodine species limited to a concentration of less than about 700 ppm so that any visible stain resulting from the application of this composition on the skin will dissipate without leaving any visible skin coloration.
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: August 13, 2002
    Assignee: Symbollon Corporation
    Inventor: Jack Kessler
  • Publication number: 20010056127
    Abstract: Non-staining topical iodine disinfecting compositions having the ability to inactivate pathogens associated with skin infections or diseases. based upon the presence of molecular iodine in a concentration above at least 15 ppm. Any other iodine species selected from the group consisting of complexed iodine and triiodide may be present with the total of such other iodine species limited to a concentration of less than about 700 ppm so that any visible stain resulting from the application of this composition on the skin will dissipate without leaving any visible skin coloration.
    Type: Application
    Filed: December 12, 2000
    Publication date: December 27, 2001
    Applicant: SYMBOLLON CORPORATION
    Inventor: Jack Kessler