Patents by Inventor Jack Kosmicki

Jack Kosmicki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation Of Endoplasmic Reticulum Aminopeptidase 2 (ERAP2)-Mediated Immune Response
    Publication number: 20230059929
    Abstract: The present disclosure provides methods of treating subjects having an immune disorder by administering a therapeutically effective amount of an Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) inhibitor to the subject, and optionally an Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) agonist or inhibitor and/or an HLA-Aw19 inhibitor, and also provides methods of identifying subjects having an increased risk for developing an MHC-I-opathy.
    Type: Application
    Filed: July 23, 2021
    Publication date: February 23, 2023
    Inventors: Sahar Gelfman, Ann Ligocki, Giovanni Coppola, Aris Baras, Arden Moscati, Eli A. Stahl, Jack A. Kosmicki, Manuel Allen Revez Ferreira, Carmelo Romano
  • Materials And Methods Of Treating MHC-1-Opathy Risk Haplotypes
    Publication number: 20220323581
    Abstract: The present disclosure provides methods of treating subjects having an immune disorder by administering to the subject a therapeutically effective amount of an Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) inhibitor in combination with an HLA-A29 or HLA-B27 inhibitory nucleic acid molecule.
    Type: Application
    Filed: April 6, 2022
    Publication date: October 13, 2022
    Inventors: Sahar Gelfman, Ann Ligocki, Giovanni Coppola, Aris Baras, Arden Moscati, Eli A. Stahl, Jack A. Kosmicki, Manuel Allen Revez Ferreira, Carmelo Romano
  • Methods Of Identifying Subjects Having An Increased Risk Of Developing A Coronavirus Infection And Treatment Thereof
    Publication number: 20220177982
    Abstract: Methods of treating subjects having a coronavirus infection, and methods of identifying subjects having an increased risk of a coronavirus infection are provided herein.
    Type: Application
    Filed: December 3, 2021
    Publication date: June 9, 2022
    Inventors: Jack Kosmicki, Julie Horowitz, Manuel Allen Revez Ferreira, Goncalo Abecasis, Aris Baras, Amy Damask