Abstract: A rotor for all systems used to circulate various single-phase or multiphase fluids, ranging from organic or non-organic solvents to CO2 in a liquid or supercritical phase in cells connected to each other by channels, the assembly being subjected to adjustable centrifugal acceleration and including precision temperature control for chemical or biochemical reactions and extractions, and purification and separation reactions and, for use in chemical and biochemical reactors. Such a rotor is formed of one or more discs stacked on top of each other, each being made up of circular sectors consisting of a circular half-sector and a circular half-sector, each being the mirror image of the other relative to the plane of the circular half-sector after they have been assembled opposite each other in a sealed manner. Their half-channels having respective links which form a link channel when the half-sectors are joined.

Abstract: A method for continuous exchange of material includes countercurrent contacting of a first fluid phase and a second fluid phase that are not completely miscible. The contacting is carried out in a single centrifugal partition chromatography (CPC) apparatus into which only the first and second fluid phases introduced. The apparatus includes a plurality of cells, each with a stationary phase immobilized and a mobile phase passing through the stationary phase. The following steps are carried out successively: a) the mobile phase is formed by the first fluid phase, and the stationary phase immobilized in the cells is formed by the second fluid phase; b) the mobile phase is formed by the second fluid phase, and the stationary phase immobilized in the cells is formed by the first fluid phase; c) repetition of the succession of steps a) and b) each step being carried out immediately after the preceding step.

Abstract: The present invention concerns a module for a photobioreactor suitable for being assembled to an identical adjacent module, comprising: —a panel having a first face and a second face, opposite the first face, the first face delimiting, with the second face of the adjacent panel, a cavity suitable for containing a culture medium when the modules are assembled, the cavity (14) having a thickness of between 1 millimetre and 2 centimetres, and —a gas injection device, capable of injecting gas bubbles into the culture medium contained in the cavity, such that the bubbles rise along the faces of the panels.

Abstract: A method is provided for extracting cellular compounds from micro-organisms. The method includes culturing the micro-organisms and extracting the cellular compounds from the micro-organisms. Each step is carried out in a continuous manner, wherein the extraction step is carried out separately from the culture step and in conditions of biocompatibility with the micro-organisms. The method further includes at least one step of recovering the cellular compounds and at least one step of recirculating the micro-organisms towards the culture step.

Abstract: The invention relates to a photoreactor (1) comprising a contained reaction chamber (15), wherein the chamber (15) is separated from the exterior by a light-capturing wall (11) and another wall (12), the capturing wall and the other wall being parallel to one another; characterized in that the photoreactor (1) additionally comprises a thermal valve (13) placed against the other wall (12) for passively controlling the increase in heat inside the chamber (15) due to the radiation passing through the capturing wall (11) in order to maintain the temperature in at least one part of the chamber (15) under a threshold temperature (Ts), the thermal valve (13) being made of a phase-change material.

Abstract: The present invention relates to a device and a method for placing immiscible fluid phases in contact with each other by means of centrifugal force, in particular in order to extract compounds from one of said phases by another phase. Said device comprises at least one contacting unit (3*) which is capable of being rotated about an axis (X?X) and which includes a plurality of cells (210, A, D) intended to be passed through consecutively by said phases, in a given flow direction, each cell being provided with two inlet/outlet channels (214 and 215) which fluidly connect the cells together in pairs and which lead into each cell, respectively, via two inlet/outlet openings, which are proximal (214a) and distal (215a) relative to the said axis, respectively.

Abstract: The invention relates to a photobioreactor (1) for the culture of cells, comprising a runoff substrate (2) having a surface inclined at an average slope along a direction of inclination (I-I) on which a solution flows and including an upstream side (21) and a downstream side (22), said solution comprising cells in suspension. The invention is characterised in that the photobioreactor (1) comprises an upflow element (3) that conveys the solution from the downstream end (22) to the upstream end (21) along an upflow direction that is substantially parallel to the direction of inclination (I-I).

Abstract: The present invention relates to a centrifugal partitioning chromatography device for separating a liquid having at least two phases, and to a centrifugal partitioning chromatography method implemented by this device. A chromatography device according to the invention comprises at least one flat ring (103) which can be rotated about its axis (X?X) of symmetry and comprises a multitude of cells (110) through which the liquid is intended to flow, each cell being provided with two input/output channels (111 and 112) that are intended to make the liquid flow from one cell to another and which open respectively via two inlet/outlet orifices (111a and 112a) of the cell on two radially internal and external sides (113 and 114) of the latter with respect to the axis of rotation.

Abstract: The present invention thus aims to propose a bioreactor which has an improved yield (concentration, productivity), which is capable of culturing microorganisms sensitive to mechanical stresses, and which is energy-saving. The subject matter of the invention is a method for culturing microorganisms in suspension in a culture medium, in which the microorganism suspension is made to flow in a channel which has means for generating mixing by Lagrangian chaos when the microorganism suspension circulates in said channel.

Abstract: The present invention relates to a centrifugal partitioning chromatography device for separating a liquid having at least two phases, and to a centrifugal partitioning chromatography method implemented by this device. A chromatography device according to the invention comprises at least one flat ring (103) which can be rotated about its axis (X?X) of symmetry and comprises a multitude of cells (110) through which the liquid is intended to flow, each cell being provided with two input/output channels (111 and 112) that are intended to make the liquid flow from one cell to another and which open respectively via two inlet/outlet orifices (111a and 112a) of the cell on two radially internal and external sides (113 and 114) of the latter with respect to the axis of rotation.

Abstract: HA method is provided for extracting cellular compounds from micro-organisms. The method includes culturing the micro-organisms and extracting the cellular compounds from the micro-organisms. Each step is carried out in a continuous manner, wherein the extraction step is carried out separately from the culture step and in conditions of biocompatibility with the micro-organisms. The method further includes at least one step of recovering the cellular compounds and at least one step of recirculating the micro-organisms towards the culture step.

Abstract: Method for sizing the cells of a centrifugal liquid-liquid chromatography “column” (CPC column) consisting of stacked discs on which the cells connected in cascade (in series) by small channels are engraved. Rotation of the stack creates a high centrifugal acceleration field which makes it possible to keep a liquid phase referred to as stationary phase motionless, whereas a mobile phase circulates along the CPC column. The cells are three-dimensional, with two dimensions (L, l) of the cells oriented in a plane substantially normal to the axis of rotation (?) of the disc and a third dimension (e) oriented in a direction substantially parallel to the axis of rotation, and selected so as to be at least equal to one of the other two dimensions (L, l), thus providing higher efficiency. When the scale of the devices has to be changed, the size of the cells is modified ensuring that, in any case, this third dimension (e) is favored so as to be as great as possible.

Abstract: Method for sizing the cells of a centrifugal liquid-liquid chromatography “column” (CPC column) consisting of stacked discs on which the cells connected in cascade (in series) by small channels are engraved. Rotation of the stack creates a high centrifugal acceleration field which makes it possible to keep a liquid phase referred to as stationary phase motionless, whereas a mobile phase circulates along the CPC column. The cells are three-dimensional, with two dimensions (L, I) of the cells oriented in a plane substantially normal to the axis of rotation (?) of the disc and a third dimension (e) oriented in a direction substantially parallel to the axis of rotation, and selected so as to be at least equal to one of the other two dimensions (L, I), thus providing higher efficiency. When the scale of the devices has to be changed, the size of the cells is modified ensuring that, in any case, this third dimension (e) is favoured so as to be as great as possible.

Abstract: This invention provides a method for separating and extracting biological products of avian origin. The method allows for the production of avian cartilages and of active ingredients which can be extracted from the cartilages thus obtained.

Abstract: The invention relates to a method of improving the transfer in an annular biological reaction chamber defined by coaxial inner and outer walls (11, 12) and in which there flows a liquid reaction medium containing a culture of microorganisms or of cells from vegetable or animal macroorganisms in suspension. At least one of the walls is an exchange wall enabling gaseous or liquid matter to be transferred or allowing light to pass through. The reaction medium is subjected to a turbulent primary flow that is helical and that under the action of centrifugal force creates rotary secondary vortices so as to encourage renewal of the culture in the vicinity of the exchange wall.

Abstract: The invention relates to a method of improving the transfer in an annular biological reaction chamber defined by coaxial inner and outer walls (11, 12) and in which there flows a liquid reaction medium containing a culture of microorganisms or of cells from vegetable or animal macroorganisms in suspension. At least one of the walls is an exchange wall enabling gaseous or liquid matter to be transferred or allowing light to pass through. The reaction medium is subjected to a turbulent primary flow that is helical and that under the action of centrifugal force creates rotary secondary vortices so as to encourage renewal of the culture in the vicinity of the exchange wall.

Abstract: A centrifuge partition chromatography device for separating a liquid into at least two phases, comprising at least one flat ring (3a) that can be rotationally driven around its axis, disposed in a substantially vertical position. Said ring (3a) comprises a plurality of cells (7) whose dimensions are greater in a first direction than the dimensions in a second direction which is substantially perpendicular to the first, disposed side by side and distributed along the periphery of said ring (3a) in addition to being connected to each other in a series by inlet and outlet ducts (15) terminating in the opposite respective ends of each cells (7) enabling the circulation of liquid. The invention is characterized in that said ducts (15) are disposed in such a way that the liquid supply jet penetrates the cells (7) in a direction that includes at least one radial component relative to the axis of rotation of said ring (3a).