Abstract: Described herein are RNA-protein fusion production methods which involve a high salt post-translational incubation step.

Abstract: Uniform-sized liposome populations can improve both the efficacy and safety of drug delivery. The present invention utilizes the techniques of extrusion with polycarbonate-membrane-based large-pore dialysis to create uniform-sized liposome populations. These uniform-sized liposome populations may comprise different sizes such that smaller liposome populations contain specific drugs that are compartmentalized within a larger liposome population. These uniform-sized liposomes can be lysed upon photoillumination and release the encapsulated drugs and/or smaller liposomes, and can be used as a new version of photodynamic therapy.

Abstract: Described herein are RNA-protein fusion production methods which involve a high salt post-translational incubation step.

Abstract: The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest.

Abstract: The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest.

Abstract: Described herein are RNA-protein fusion production methods which involve a high salt post-translational incubation step.

Abstract: Described herein are methods and reagents for the selection of protein molecules that make use of RNA-protein fusions.

Abstract: Described herein are RNA-protein fusion production methods which involve a high salt post-translational incubation step.

Abstract: The invention provides peptides with high affinity for streptavidin. These peptides may be expressed as part of fusion proteins to facilitate the detection, quantitation, and purification of proteins of interest.

Abstract: Described herein are methods and reagents for the selection of protein molecules that make use of RNA-protein fusions.

Abstract: Described herein are RNA-protein fusion production methods which involve a high salt post-translational incubation step.

Abstract: Described herein are methods and reagents for the selection of protein molecules that make use of RNA-protein fusions.

Abstract: A novel 3′-terminus modified nucleic acid and a method of making such product using a synthetic nucleotide template with a defined overhang nucleotide are disclosed. The method allows an efficient incorporation of a single modified nucleotide onto the 3′-terminus of the nucleic acid.

Abstract: Described herein are methods and reagents for the selection of protein molecules that make use of RNA-protein fusions.

Abstract: Described herein are methods and reagents for the selection of protein molecules that make use of RNA-protein fusions.

Abstract: The invention features nucleic acid molecules and, in particular, DNA molecules having catalytic activity, as well as methods for obtaining and using such nucleic acid molecules.

Abstract: The invention concerns a method for creating, identifying, and isolating ribozymes capable of binding a selected ligand and catalyzing a reaction involving the selected ligand. The method entails sequential selections for ligand binding molecules and catalytic molecules. The invention also includes novel ribozymes produced by these methods.

Abstract: There are provided nucleic acid hybridization assays for RNA targets using RNA binary probes and a ribozyme ligase that is a stringent RNA-directed RNA ligase. Preferred assays include exponential amplification for signal generation. Tetrahymena ribozyme ligase is a preferred ligase for use in this invention. It may be tethered to hold it close to the ligation junction. One assay according to this invention is a "tethered ligase chain reaction." Also provided are kits for performing assays according to the invention.

Abstract: Disclosed are single-stranded DNA molecules which bind adenosine or an adenosine-5'-phosphate and methods for their production and isolation. Also disclosed are methods for producing and isolating related catalytic DNA molecules.

Abstract: The present invention provides a process for increasing the rate of production of carbon dioxide, ethanol and other fermentation products such as citric acid, produced by yeast such as Saccharomyces cerevisiae during fermentation, and decreasing biomass production by regulating the rate of glycolysis indirectly through changing the energy balance of the cell, i.e., by reducing intracellular ATP levels. Modifications for so altering the glycolysis rate involve the use of either a regulated ATP hydrolysis within the cell or a regulated leakage of ATP from the cell.