Patents by Inventor Jackeline Campos

Jackeline Campos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybrid interferon/interferon tau proteins, compositions and methods of use
    Patent number: 7232563
    Abstract: The present invention relates to hybrid interferon fusion proteins formed of an interferon-? protein where the C-terminal region of the interferon-? protein is replaced by a C-terminal region of interferon-?. Also described are nucleic acid sequences encoding the interferon fusion proteins, expression vectors containing such sequences, and therapeutic applications of the interferon fusion proteins. The therapeutic applications include antiviral, anticellular proliferation, and anti-inflammatory applications. One advantage of the interferon fusion polypeptides of the present invention is that they have lower cytotoxic side effects when used to treat cells.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: June 19, 2007
    Assignee: Pepgen Corporation
    Inventors: Lorelie H. Villarete, Jackeline Campos, Wayne Li
  • Hybrid interferon/interferon tau proteins, compositions and methods of use
    Publication number: 20030130486
    Abstract: The present invention relates to hybrid interferon fusion proteins formed of an interferon-&agr; protein where the C-terminal region of the interferon-&agr; protein is replaced by a C-terminal region of interferon-&tgr;. Also described are nucleic acid sequences encoding the interferon fusion proteins, expression vectors containing such sequences, and therapeutic applications of the interferon fusion proteins. The therapeutic applications include antiviral, anticellular proliferation, and anti-inflammatory applications. One advantage of the interferon fusion polypeptides of the present invention is that they have lower cytotoxic side effects when used to treat cells.
    Type: Application
    Filed: August 12, 2002
    Publication date: July 10, 2003
    Inventors: Lorelie H. Villarete, Jackeline Campos, Wayne Li
  • Low-toxicity human interferon-alpha analogs
    Patent number: 6204022
    Abstract: The invention describes a method of reducing the cytotoxicity of interferon-alpha by making defined amino acid substitutions in the N-terminal portion of the polypeptide sequence. Also described are human interferon-alpha analogs with low cytotoxicity, and therapeutic applications of the low toxicity interferon-alpha analogs.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: March 20, 2001
    Assignee: Pepgen Corporation and University of Florida
    Inventors: Howard M. Johnson, Carol H. Pontzer, Prem S. Subramaniam, Lorelie H. Villarete, Jackeline Campos