Patents by Inventor Jackie D. Corbin

Jackie D. Corbin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for phosphodiesterase function
    Patent number: 7217527
    Abstract: The present invention provides filter-based assays for measuring binding of compounds to phosphodiesterases (PDEs). The assay permits stoichiometric binding of compounds to PDEs, thereby providing a highly sensitive measure of a PDE binding and inhibition.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: May 15, 2007
    Assignee: Vanderbilt University
    Inventors: Jackie D. Corbin, Sharron H. Francis
  • Assay for phosphodiesterase function
    Publication number: 20040266783
    Abstract: The present invention provides filter-based assays for measuring binding of compounds to phosphodiesterases (PDEs). The assay permits stoichiometric binding of compounds to PDEs, thereby providing a highly sensitive measure of a PDE binding and inhibition.
    Type: Application
    Filed: April 15, 2004
    Publication date: December 30, 2004
    Applicant: Vanderbilt University
    Inventors: Jackie D. Corbin, Sharron H. Francis
  • Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
    Publication number: 20030054992
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Application
    Filed: April 3, 2002
    Publication date: March 20, 2003
    Applicant: ICOS Corporation
    Inventors: Joseph A. Beavo, Jackie D. Corbin, Kenneth M. Ferguson, Sharron H. Francis, Ann Kadlecek, Kate Loughney, Linda M. McAllister-Lucas, William K. Sonnenburg, Melissa K. Thomas
  • Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
    Patent number: 6037119
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 14, 2000
    Assignee: Board of Regents of the University of Washington
    Inventors: Joseph A. Beavo, Jackie D. Corbin, Kenneth M. Ferguson, Sharron H. Francis, Ann Kadlecek, Kate Loughney, Linda M. McAllister-Lucas, William K. Sonnenburg, Melissa K. Thomas
  • Antibodies to cGMP-binding, cGMP-specific phospodiesterase
    Patent number: 5955583
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Antibodies to the cGMP-binding, cGMP-stimulated phosphodiesterase are disclosed. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 21, 1999
    Assignees: ICOS Corporation, Board of Regents of the University of Washington, Vanderbilt University
    Inventors: Joseph A. Beavo, Jackie D. Corbin, Kenneth M. Ferguson, Sharron H. Francis, Ann Kadlecek, Kate Loughney, Linda M. McAllister-Lucas, William K. Sonnenburg, Melissa K. Thomas
  • Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
    Patent number: 5702936
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: December 30, 1997
    Assignees: ICOS Corporation, Vanderbilt University, Board of Regents of the University of Washington
    Inventors: Joseph A. Beavo, Jackie D. Corbin, Kenneth M. Ferguson, Sharron H. Francis, Ann Kadlecek, Kate Loughney, Linda M. McAllister-Lucas, William K. Sonnenburg, Melissa K. Thomas
  • Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
    Patent number: 5652131
    Abstract: The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 29, 1997
    Assignees: ICOS Corporation, Vanderbilt University, Board of Regents of the University of Washington
    Inventors: Joseph A. Beavo, Jackie D. Corbin, Kenneth M. Ferguson, Sharron H. Francis, Ann Kadlecek, Kate Loughney, Linda M. McAllister-Lucas, William K. Sonnenburg, Melissa K. Thomas