Patents by Inventor Jackie LE

Jackie LE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrazolo[1,5-?]pyrimidines as CRF receptor antagonists
    Patent number: 12686680
    Abstract: Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH).
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: July 21, 2026
    Assignee: Neurocrine Biosciences, Inc.
    Inventors: Neil J. Ashweek, John P. Williams, Lev Alexander Zegelman, Christina Marie Costa, Scott Stirn, Shawn Branum, Jackie Le, John Lloyd Tucker, Brian M. Cochran, David Kucera, Donald Hettinger, Max A. Mellmer
  • CRF RECEPTOR ANTAGONISTS AND METHODS OF USE
    Publication number: 20230065034
    Abstract: Compounds are provided herein that antagonize corticotropin-releasing factor (CRF) receptors, in particular CRF receptor 1 (CRF1), as well as related preparations, compositions and methods for treating diseases and/or disorders that would benefit from the same such as congenital adrenal hyperplasia (CAH).
    Type: Application
    Filed: December 1, 2020
    Publication date: March 2, 2023
    Inventors: Neil J. ASHWEEK, John P. WILLIAMS, Lev Alexander ZEGELMAN, Christina Marie COSTA, Scott STIRN, Shawn BRANUM, Jackie LE, John Lloyd TUCKER, Brian M. COCHRAN, David KUCERA, Donald HETTINGER, Max A. MELLMER
  • PROCESSES FOR THE SYNTHESIS OF VALBENAZINE
    Publication number: 20220363680
    Abstract: The present application relates to processes for making (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b -hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl (S)-2-amino-3-methylbutanoate di(4-methylbenzenesulfonate), which is an inhibitor of vesicular monoamine transporter 2 (VMAT2) useful in the treatment of hyperkinetic movement disorders such as tardive dyskinesia (TD).
    Type: Application
    Filed: September 11, 2020
    Publication date: November 17, 2022
    Inventors: John TUCKER, David KUCERA, Donald HETTINGER, Brian M. COCHRAN, Shawn BRANUM, Jackie LE, Kevin MCGEE