Patents by Inventor Jackie S. Bodnar

Jackie S. Bodnar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotide pairs for multiplexed binding assays
    Patent number: 7195875
    Abstract: The invention is an oligonucleotide-based assay system and kit useful for sorting, detecting, and identifying analytes. The system utilizes complementary oligonucleotide pairs in which one oligonucleotide of each pair is immobilized to a solid substrate and the other oligonucleotide has an analyte binding agent attached to it. The different oligonucleotide pairs hybridize at substantially the same rate, have substantially the same Tm, have nucleotide sequences designed to minimize cross-hybridization between different pairs, and hybridize together relatively rapidly at ambient temperatures without detectable cross-hybridization.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: March 27, 2007
    Assignee: Beckman Coulter, Inc.
    Inventors: Daniel A. Keys, Parameswara Meda Reddy, Jackie S. Bodnar, Firdous Farooqui
  • Oligonucleotide pairs for multiplexed binding assays
    Publication number: 20040209261
    Abstract: The invention is an oligonucleotide-based assay system and kit useful for sorting, detecting, and identifying analytes. The system utilizes complementary oligonucleotide pairs in which one oligonucleotide of each pair is immobilized to a solid substrate and the other oligonucleotide has an analyte binding agent attached to it. The different oligonucleotide pairs hybridize at substantially the same rate, have substantially the same Tm, have nucleotide sequences designed to minimize cross-hybridization between different pairs, and hybridize together relatively rapidly at ambient temperatures without detectable cross-hybridization.
    Type: Application
    Filed: April 18, 2003
    Publication date: October 21, 2004
    Inventors: Daniel A. Keys, Parameswara Meda Reddy, Jackie S. Bodnar, Firdous Farooqui
  • Gene and sequence variation associated with lipid disorder
    Publication number: 20030064372
    Abstract: The present invention relates to the discovery of gene and its sequence variation associated with lipid disorder and cancer. The present invention also relates to the study of metabolic pathways and cellular mechanisms to identify other genes, receptors, and relationships that contribute to lipid disorder and cancer. The present invention also relates to germline or somatic sequence variation and its use in the diagnosis and prognosis of predisposition to lipid disorder and cancer. The present invention also provides primers or probes specific for the detection and analysis of such sequence variation. The present invention also relates to methods to screen drugs for inhibition or restoration of gene function as an anti-lipid disorder or anti-cancer therapy. Finally, the present invention relates to other anti-lipid disorder or anti-cancer therapies, such as gene therapy, protein replacement therapy, etc.
    Type: Application
    Filed: September 7, 2001
    Publication date: April 3, 2003
    Inventors: Jackie S. Bodnar, Lawrence W. Castellani, Aurobindo Chatterjee, Pieter de Jong, Aldons JAKE Lusis, Jeff Ohmen, David Ross, Sherrie Tafuri, Chenyan Wu
  • Gene and sequence variation associated with cancer
    Publication number: 20030054418
    Abstract: The present invention relates to the discovery of gene and its sequence variation associated with lipid disorder and cancer. The present invention also relates to the study of metabolic pathways and cellular mechanisms to identify other genes, receptors, and relationships that contribute to lipid disorder and cancer. The present invention also relates to germline or somatic sequence variation and its use in the diagnosis and prognosis of predisposition to lipid disorder and cancer. The present invention also provides primers or probes specific for the detection and analysis of such sequence variation. The present invention also relates to methods to screen drugs for inhibition or restoration of gene function as an anti-lipid disorder or anti-cancer therapy. Finally, the present invention relates to other anti-lipid disorder or anti-cancer therapies, such as gene therapy, protein replacement therapy, etc.
    Type: Application
    Filed: September 7, 2001
    Publication date: March 20, 2003
    Inventors: Jackie S. Bodnar, Lawrence W. Castellani, Aurobindo Chatterjee, Pieter de Jong, Aldons Jake Lusis, Jeff Ohmen, David Ross, Sherrie Tafuri, Chenyan Wu