Abstract: An apparatus for processing a biological and/or chemical sample in a liquid droplet is provided. The apparatus includes a processing compartment, a base and at least one circumferential wall. The processing compartment is defined by at least a part of the base, at least a part of the circumferential wall and an inlet member. The inlet member is located on top of the processing compartment, and includes at least one droplet inlet channel, which extends through the inlet member and includes a contraction between the inlet opening of the droplet inlet channel to the environment and the outlet opening to the processing compartment.

Abstract: An apparatus for processing a biological and/or chemical sample in a liquid droplet (1) is provided. The apparatus includes a processing compartment (20), a base (21) and at least one circumferential wall (25). The processing compartment (20) is defined by at least a part of the base (21), at least a part of the circumferential wall (25) and an inlet member (4). The inlet member (4) is located on top of the processing compartment (20), and includes at least one droplet inlet channel (3), which extends through the inlet member (4) and includes a contraction (2) between the inlet opening (28) of the droplet inlet channel (3) to the environment and the outlet opening (27) to the processing compartment (20). There is furthermore provided a method of processing a biological and/or chemical sample in a liquid droplet (1).

Abstract: It is provided a Near Infrared Sensitive (NIR-sensitive) nanoparticle complex comprising a NIR-sensitive nanoparticle and surfactant(s) adsorbed on the nanoparticle, wherein the surfactant is at least one surfactant selected from: wherein X=1-9; Y=0-9; n=0-9; Z=1-9; W=0-9; m=0-9; each of R1, R2, R3 and R4, if present, is H, substituted or unsubstituted C1-C6 alkyl, substituted or unsubstituted C1-C6 aryl, HS, COOH, NH2 or OH; R5 is COOH, NH2 or OH; with the proviso that n+m is <10; (b) an amino acid having the structure in (a), wherein X=1; Y=2; Z=1; W=1; R1, R2 and R4 are not present; R3 is NH2; and R5 is COOH; or (c) a peptide, wherein the peptide comprise at least one amino acid (b). Further, it is provided a NIR-sensitive nanoparticle complex(es) having biomolecule(s), for example drug(s), loaded on the surfactant(s).