Patents by Inventor Jacob A. Aten

Jacob A. Aten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120022026
    Abstract: The present invention relates to a method of treating or preventing hyperproliferative disease in a body tissue of a subject, comprising the steps of administering to a subject in need thereof a therapeutically effective amount of an agent that induces double strand breaks in the DNA of the hyperproliferative cells of said body tissue; and subjecting the hyperproliferative cells of said body tissue prior to, simultaneously with or subsequent to step a) to hyperthermia to thereby induce in said cells the degradation, inhibition and/or inactivation of BRCA2.
    Type: Application
    Filed: January 13, 2010
    Publication date: January 26, 2012
    Applicants: ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM, ACADEMISCH MEDISCH CENTRU BIJ DE UNIVERSITEIT VAN AMSTERDAM
    Inventors: Przemyslaw Krawczyk, Jacob A. Aten, Roland Kanaar, Jeroen Essers