Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: The present invention provides a combination of a Type I protein arginine methyltransferase (Type I PRMT) inhibitor and a Type II protein arginine methyltransferase (Type II PRMT) inhibitor. The present invention also provides methods for treating cancer in a human in need thereof, the methods comprising administering to the human a combination of a Type I PRMT inhibitor and a Type II PRMT inhibitor, together with at least one of: a pharmaceutically acceptable carrier and a pharmaceutically acceptable diluent, thereby treating the cancer in the human. The present invention further provide a pharmaceutical composition comprising a therapeutically effective amount of a Type I PRMT inhibitor and a second pharmaceutical composition comprising a therapeutically effective amount of a Type II PRMT inhibitor.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: The present invention provides a combination of a Type I protein arginine methyltransferase (Type I PRMT) inhibitor and a Type II protein arginine methyltransferase (Type II PRMT) inhibitor. The present invention also provides methods for treating cancer in a human in need thereof, the methods comprising administering to the human a combination of a Type I PRMT inhibitor and a Type II PRMT inhibitor, together with at least one of: a pharmaceutically acceptable carrier and a pharmaceutically acceptable diluent, thereby treating the cancer in the human. The present invention further provide a pharmaceutical composition comprising a therapeutically effective amount of a Type I PRMT inhibitor and a second pharmaceutical composition comprising a therapeutically effective amount of a Type II PRMT inhibitor.

Abstract: This document relates to hardware protection of differential privacy techniques. One example obtains multiple instances of encrypted telemetry data within a secure enclave and processes the encrypted telemetry data to obtain multiple instances of unencrypted telemetry data. The example also processes, within the secure enclave, the multiple instances of unencrypted telemetry data to obtain a perturbed aggregate. The example also releases the perturbed aggregate from the secure enclave.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A system includes determination of a plurality of meta-copysets of a plurality of storage devices, each of the meta-copysets including a first number of storage devices, determination of a first copyset of a second number of storage devices from a first one of the meta-copysets, where the second number is less than the first number, storage of first data in a fault-tolerant format using the first copyset, determination to migrate the first data from a first storage device of the first copyset, and, in response to the determination to migrate the first data, determine a second copyset of the second number of storage devices including a storage device from the first meta-copyset which is not in the first copyset, and the storage devices of the first copyset except for the first storage device of the first copyset and storage of the first data in a fault-tolerant format using the second copyset.

Abstract: This invention relates to methods of treating cancer in a subject in need thereof, e.g., in a human in need thereof, comprising determining the level of 5-Methylthioadenosine phosphorylase (MTAP) polynucleotide or polypeptide or the presence or absence of a mutation in MTAP in a sample from the human, and administering to the human an effective amount of a Type I protein arginine methyltransferase (Type I PRMT) inhibitor if the level of the MTAP polynucleotide or polypeptide is decreased relative to a reference or if a mutation in MTAP polynucleotide or polypeptide is present, thereby treating the cancer in the human.

Abstract: A system includes determination of a plurality of meta-copysets of a plurality of storage devices, each of the meta-copysets including a first number of storage devices, determination of a first copyset of a second number of storage devices from a first one of the meta-copysets, where the second number is less than the first number, storage of first data in a fault-tolerant format using the first copyset, determination to migrate the first data from a first storage device of the first copyset, and, in response to the determination to migrate the first data, determine a second copyset of the second number of storage devices including a storage device from the first meta-copyset which is not in the first copyset, and the storage devices of the first copyset except for the first storage device of the first copyset and storage of the first data in a fault-tolerant format using the second copyset.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: This document relates to hardware protection of differential privacy techniques. One example obtains multiple instances of encrypted telemetry data within a secure enclave and processes the encrypted telemetry data to obtain multiple instances of unencrypted telemetry data. The example also processes, within the secure enclave, the multiple instances of unencrypted telemetry data to obtain a perturbed aggregate. The example also releases the perturbed aggregate from the secure enclave.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.

Abstract: A human-computer interface system including: a sensor configured to transduce the location of a finger of a hand of a user; an exoskeleton configured to exchange mechanical energy with the finger; and an interface garment, including: an interface laminate coupled to a counterpressure assembly, configured to stimulate the user by applying a pressure to the finger; a first plurality of tactile actuators configured to apply a pressure to a finger of the user; and a second plurality of tactile actuators configured to apply a pressure to a palm of the hand of the user.

Abstract: A human-computer interface system including: a sensor configured to transduce the location of a finger of a hand of a user; an exoskeleton including: a kinematic termination configured to exchange mechanical energy with the finger of the hand, a force transmission element, an actuator, and a mechanical ground; and an interface garment, including: an interface laminate coupled to a counterpressure assembly, configured to stimulate the user by applying a pressure to the finger.

Abstract: A human-computer interface system having an exoskeleton including a plurality of structural members coupled to one another by at least one articulation configured to apply a force to a body segment of a user, the exoskeleton comprising a body-borne portion and a point-of-use portion; the body-borne portion configured to be operatively coupled to the point-of-use portion; and at least one locomotor module including at least one actuator configured to actuate the at least one articulation, the at least one actuator being in operative communication with the exoskeleton.