Patents by Inventor Jacob Brandt

Jacob Brandt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulin and IGF-1 Receptor Agonists and Antagonists
    Publication number: 20090192072
    Abstract: Peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors with either agonist or antagonist activity and identified from various peptide libraries are disclosed. This invention also identifies at least two different binding sites, which are present on insulin and insulin-like growth factor receptors, and which selectively bind the peptides of this invention. As agonists, certain of the peptides of this invention may be useful for development as therapeutics to supplement or replace endogenous peptide hormones. The antagonists may also be developed as therapeutics.
    Type: Application
    Filed: November 21, 2008
    Publication date: July 30, 2009
    Applicants: Novo Nordisk A/S, Antyra Inc. (formerly DGI Bio Technologies)
    Inventors: Renuka Pillutla, Renee Brissette, Arthur J. Blume, Lauge Schaffer, Jacob Brandt, Neil I. Goldstein, Jane Spetzler, Soren Ostergaard, Per Hertz Hansen
  • Isulin and IGF-1 receptor agonists and antagonists
    Publication number: 20030236190
    Abstract: Peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors with either agonist or antagonist activity and identified from various peptide libraries are disclosed. This invention also identifies at least two different binding sites, which are present on insulin and insulin-like growth factor receptors, and which selectively bind the peptides of this invention. As agonists, certain of the peptides of this invention may be useful for development as therapeutics to supplement or replace endogenous peptide hormones. The antagonists may also be developed as therapeutics.
    Type: Application
    Filed: September 24, 2002
    Publication date: December 25, 2003
    Inventors: Renuka Pillutla, Renee Brissette, Arthur J. Blume, Lauge Schaffer, Jacob Brandt, Neil I. Goldstein, Jane Spetzler, Soren Ostergaard, Per Hertz Hansen
  • Quantitative analysis of hexose-monophosphates from biological samples
    Patent number: 6451611
    Abstract: The invention is for a method of quantitatively analysing the hexose monophosphate (HMP) composition of a biological sample, preferably a dried blood sample, using tandem mass spectrometry and for a method for quantitatively analysing the abundance of amino acids acylcarnitines and HMP from the same biological sample (such as a dried blood spot sample). The method is useful in screening infants for galactosemia and can be integrated with a method of screening for disorders in the metabolism of amino acids, organic acids and fatty acids.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: September 17, 2002
    Assignee: Statens Serum Institute
    Inventors: Henrik Simonsen, Ulrich Glümer Jensen, Niels Jacob Brandt, Ernst Christensen
  • Process for making desired polypeptides in yeast
    Patent number: 6183989
    Abstract: The invention describes a process for making desired polypeptides in yeast. The desired products are expressed as leader bound polypeptides connected by means of a monobasic processing site. The desired polypeptide is cleaved from the leader either in vivo or in vitro by enzymatic cleavage.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: February 6, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Jacob Brandt, Knud Vad