Patents by Inventor Jacob C. Schwartz

Jacob C. Schwartz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATING GENE EXPRESSION WITH agRNA AND GAPMERS TARGETING ANTISENSE TRANSCRIPTS
    Publication number: 20150064709
    Abstract: Gene expression is selectively modulated in the genome of a mammalian cell determined to be in need thereof by determining the presence of an encoded antisense transcript overlapping a promoter of the target gene; contacting the transcript with an agRNA or gapmer complementary to a portion of the transcript upstream relative to the transcription start site of the gene; and detecting a resultant modulation of expression of the target gene.
    Type: Application
    Filed: September 10, 2014
    Publication date: March 5, 2015
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jacob C. SCHWARTZ, Scott T. YOUNGER, Bethany A. JANOWSKI, David R. COREY
  • Modulating Gene Expression With agRNA and Gapmers Targeting Antisense Transcripts
    Publication number: 20120288869
    Abstract: Gene expression is selectively modulated in the genome of a mammalian cell determined to be in need thereof by determining the presence of an encoded antisense transcript overlapping a promoter of the target gene; contacting the transcript with an agRNA or gapmer complementary to a portion of the transcript upstream relative to the transcription start site of the gene; and detecting a resultant modulation of expression of the target gene.
    Type: Application
    Filed: July 3, 2012
    Publication date: November 15, 2012
    Inventors: Jacob C. Schwartz, Scott T. Younger, Bethany A. Janowski, David R. Corey
  • Modulating Gene Expression with agRNA and Gapmers Targeting Antisense Transcripts
    Publication number: 20090092988
    Abstract: Gene expression is selectively modulated in the genome of a mammalian cell determined to be in need thereof by determining the presence of an encoded antisense transcript overlapping a promoter of the target gene; contacting the transcript with an agRNA or gapmer complementary to a portion of the transcript upstream relative to the transcription start site of the gene; and detecting a resultant modulation of expression of the target gene.
    Type: Application
    Filed: October 6, 2008
    Publication date: April 9, 2009
    Inventors: Jacob C. Schwartz, Scott T. Younger, Bethany A. Janowski, David R. Corey