Abstract: Pyrrolidine main protease inhibitors are described that are effective as antiviral compounds.

Abstract: A folded slab waveguide laser having a hybrid waveguide-unstable resonator cavity. Multiple slab waveguides of thickness ‘t’ supporting vertical waveguide modes are physically arranged above one another in a stack and optically arranged in series through one or more cavity folding assemblies with curved mirrors. A gain medium such as a gas is arranged in each slab. Each cavity folding assembly is designed to redirect the radiation beam emitted from one slab waveguide into the next waveguide and also at the same time to provide a focus for the radiation beam so that a selected vertical waveguide mode (or modes) is (or are) coupled efficiently into the next slab.

Abstract: This invention provides a hingeless safe door assembly that can be flush mounted in a recessed safe compartment built into a wall or floor. Thus, a frame and flush cover plate holds the door assembly recessed away from the wall or floor for access to locking and latching mechanisms integral in the removable door.A latch bolt operating mechanism axially moves a master bolt, and other slave bolts are similarly axially moved by a pivoted lever that engages both the master and slave bolt for concurrent axial movement between latched and unlatched positions.