Abstract: The invention relates to compounds of formula (I): or a salt thereof, wherein R1, G, L1, L2, L3, and Y are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are inhibitors of one, or both of, ?v?1 integrin and ?v?6 integrin that are useful for treating fibrosis such as in nonalcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Abstract: Techniques and mechanisms for providing communications which facilitate link training. In an embodiment, a memory controller includes, or couples to, trainer circuitry which is configured to provide instructions to generate memory access commands. The instructions are accessed at the circuitry in response to an indication that link training is performed, where the accessing is independent of communication with a processor coupled to the memory controller. Based on the instructions, memory access commands are communicated via a link between the memory controller and a memory device. Link training is performed based on an evaluation of one or more characteristics of the link communications. In another embodiment, memory access commands are generated, based on the instructions, while a validity of data at the memory device is maintained.

Abstract: Techniques and mechanisms for providing communications which facilitate link training. In an embodiment, a memory controller includes, or couples to, trainer circuitry which is configured to provide instructions to generate memory access commands. The instructions are accessed at the circuitry in response to an indication that link training is performed, where the accessing is independent of communication with a processor coupled to the memory controller. Based on the instructions, memory access commands are communicated via a link between the memory controller and a memory device. Link training is performed based on an evaluation of one or more characteristics of the link communications. In another embodiment, memory access commands are generated, based on the instructions, while a validity of data at the memory device is maintained.

Abstract: A method and apparatus for recording data at specific locations on a DVD includes selectively detecting the occurrence of wobble sync during a window computed from previous occurrences of wobble sync and eight-to-fourteen modulation sync. The method and apparatus also uses a phase-locked loop to recover the wobble signal, including wobble sync, and computes phase drift between wobble sync and eight-to-fourteen modulation sync and applies a compensation profile, compatible with a read clock phase-locked loop, to the wobble phase-locked loop.

Abstract: A phase measurement system for measuring phase between an input signal having a frequency and a reference signal having a substantially different frequency includes: a phase comparator having an output representing a time between a crossing of a first threshold by a clock derived from the reference signal and a predetermined time along an interval from a first sample to a second sample, where the input signal crosses a second threshold on the interval; an interpolator having an output indicative of an interpolated time of the second-threshold-crossing on the interval in the input signal; and a phase calculator which computes the phase difference by combining the phase comparator output and the interpolator output.

Abstract: A phase measurement system for measuring a phase difference between an input signal and a reference signal, comprises: a phase comparator having a first input receiving a first sample of the input signal and a second sample of the input signal and having a second input receiving a clock derived from the reference signal, the phase comparator having an output representing a time between a crossing of a first threshold by the clock and a predetermined time along an interval from the first sample to the second sample where the input signal crosses a second threshold on the interval; an interpolator coupled to the first input and having an output indicative of an interpolated time of the second-threshold-crossing on the interval in the input signal; and a phase calculator coupled to the phase comparator output and the interpolator output and which computes the phase difference by combining the phase comparator output and the interpolator output.

Abstract: A method and apparatus for recording data at specific locations on a DVD includes selectively detecting the occurrence of wobble sync during a window computed from previous occurrences of wobble sync and eight-to-fourteen modulation sync. The method and apparatus also uses a phase-locked loop to recover the wobble signal, including wobble sync, and computes phase drift between wobble sync and eight-to-fourteen modulation sync and applies a compensation profile, compatible with a read clock phase-locked loop, to the wobble sync phase-locked loop.

Abstract: In a device that utilizes a memory device, the access bandwidth of the memory device is efficiently utilized by determining a set of operations to be performed on information stored in the memory device, and sorting the operations into an order so as to minimize the number of accesses to the memory device to perform the operations. The sorted operations are then performed in that order. An example of such a device is an error correction decoder, such as for use with an optical disk reader or player. The error correction decoder generates error correction data, representing error correction operations, and sorts the error correction data into multiple sets, each set for correcting the errors in a respective row of an ECC block stored in an external buffer. The error correction operations are then performed row by row.

Abstract: Apparatus and methods are provided for using a single multi-element detector and multi-channel signal conditioning circuitry to simultaneously read multiple tracks from either a CD disk or a DVD disk. The multi-element detector has a staggered arrangement and includes elongated detector elements, so that multiple reading beams reflected from multiple tracks of a CD disk are projected onto the detector, as are multiple reading beams reflected from multiple tracks of a DVD disk. The multi-channel signal conditioning circuitry conditions the signals produced by the multi-element detector, and produces signals for each of the tracks that is simultaneously read, as well as a tracking error signal, a focus error signal, a magnification error signal, and signals useful for reading DVD-RAM disks and for rapidly accessing tracks on an optical disk.

Abstract: Methods and apparatus are provided for detecting and correcting magnification errors while simultaneously reading or writing multiple data tracks with a multi-beam optical disk drive. An optical head for the optical disk drive includes a plurality of laser diodes that generate multiple light beams for reading from or writing to the optical disk, means for detecting a magnification error, and means for compensating for the magnification error to align the multiple light beams with multiple data tracks. A number of opto-mechanical systems are provided for correcting the magnification errors in the beams.

Abstract: Methods and apparatus are provided for synchronously reading data from multiple tracks of an optical disk using multiple illumination beams. Circuitry is provided for use with a photodetector array to read and buffer data in parallel from the multiple adjacent tracks, while asynchronously providing processed data to a host processor. Circuitry is further provided for concurrently processing the signals read from the multiple data tracks to recover the data stored in the tracks.

Abstract: Methods and apparatus are provided for synchronously reading data from multiple tracks of an optical disk using multiple illumination beams. Circuitry is provided for use with a photodetector array to read and buffer data in parallel from the multiple adjacent tracks, while asynchronously providing processed data to a host processor. Circuitry is further provided for correcting phase errors resulting from variations in the linear velocity of the tracks being read, depending upon the radial position of the tracks.

Abstract: Methods and apparatus are provided for simultaneously reading data from multiple tracks of an optical disk at a high rate. Circuitry is provided for generating a reference data clock independently of spindle motor speed and the spindle motor speed servo circuitry. Circuitry is also provided for deriving individual track data clocks from the reference data clock, while correcting for phase and frequency errors resulting from variations in the linear velocity of the tracks being read, depending upon the radial position of the tracks.

Abstract: Methods and apparatus are provided for synchronously reading data from multiple tracks of an optical disk using multiple illumination beams. Circuitry is provided for use with a photodetector array to read and buffer data in parallel from the multiple adjacent tracks, while asynchronously providing processed data to a host processor. Circuitry is further provided for correcting phase errors resulting from variations in the linear velocity of the tracks being read, depending upon the radial position of the tracks.

Abstract: Methods and apparatus are provided for improving optical drive access times using a detector having multiple sensing elements to sense and count disk tracks. The detector may be oriented either radially or tangentially with respect to the disk radius, and either capable of sensing more than one disk location simultaneously or have a length greater than the maximum distance between detectable features of the disk.

Abstract: Methods and apparatus are provided for simultaneously reading data from multiple tracks of an optical disk at a high rate. Circuitry is provided for generating a reference data clock independently of spindle motor speed and the spindle motor speed servo circuitry. Circuitry is also provided for deriving individual track data clocks from the reference data clock, while correcting for phase and frequency errors resulting from variations in the linear velocity of the tracks being read, depending upon the radial position of the tracks.

Abstract: Focussing system methods and apparatus are provided for apparatus capable of simultaneously reading multiple tracks of an optical disk. Astigmatism introduced by a cylindrical lens disposed adjacent to the light source, or before the focus detectors arranged at the edge of a wide-area field of illumination, is used to compute an error signal corresponding to the degree of out-of-focus, which error signal is provided to a servo-system that moves the objective lens to correct the focus. An alternative embodiment employs a pair of focus detectors and a pair of micro-lenses having different focal lengths that directs the reflected light onto the focus detectors to generate a focus correction signal. Further alternative embodiments of employing the astigmatism method of focussing are described.

Abstract: Focussing system methods and apparatus are provided for apparatus capable of simultaneously reading multiple tracks of an optical disk. Astigmatism introduced by a cylindrical lens disposed adjacent to the light source, or before the focus detectors arranged at the edge of a wide-area field of illumination, is used to compute an error signal corresponding to the degree of out-of-focus, which error signal is provided to a servo-system that moves the objective lens to correct the focus. An alternative embodiment employs a pair of focus detectors and a pair of micro-lenses having different focal lengths that directs the reflected light onto the focus detectors to generate a focus correction signal. Further alternative embodiments of employing the astigmatism method of focussing are described.

Abstract: Methods and apparatus are provided for simultaneously reading data from multiple tracks of an optical disk at a high rate. Circuitry is provided for use with a detector matrix to read and buffer data in parallel from the multiple adjacent tracks, while asynchronously providing processed data to a host processor. Circuitry is also provided for electronic tracking of tracks on the optical disk and for reducing cross-talk between adjacent tracks. Circuitry is further provided for correcting phase errors resulting from variations in the linear velocity of the tracks being read, depending upon the radial position of the tracks.