Patents by Inventor Jacob Haling

Jacob Haling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination therapies
    Patent number: 12280055
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SOS1 inhibitor and a KRas G12C inhibitor, pharmaceutical compositions comprising a such compositions, kits comprising such compositions and methods of use therefor.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: April 22, 2025
    Assignee: MIRATI THERAPEUTICS, INC.
    Inventors: Jacob Haling, John Michael Ketcham, Shilpi Khare
  • COMBINATION THERAPIES
    Publication number: 20250032497
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SOS1 inhibitor and a KRas G12C inhibitor, pharmaceutical compositions comprising a such compositions, kits comprising such compositions and methods of use therefor.
    Type: Application
    Filed: October 1, 2024
    Publication date: January 30, 2025
    Inventors: Jacob Haling, John Michael Ketcham, Shilpi Khare
  • Apparatus and method for controlling unit specific junction temperature with high temporal resolution for concurrent central processing unit (CPU) core testing
    Patent number: 11808813
    Abstract: An apparatus includes a processor configured to control an automatic test equipment (ATE) to measure one or more parameters of a current test instance for testing a device under test (DUT), during execution of the current test instance on the DUT, and determine, based on the measured one or more parameters, one or more controls for controlling a temperature of a thermal head connected to the DUT so that a junction temperature of the DUT corresponds to a predetermined test temperature. The processor is further configured to control the temperature of the thermal head, based on the determined one or more controls.
    Type: Grant
    Filed: March 11, 2022
    Date of Patent: November 7, 2023
    Assignee: Intel Corporation
    Inventors: Mahesh Deshmane, Shoujie He, Christopher Wade Ackerman, Jacob Hales, Johnny Mata Vega, Joseph Zearing
  • COMBINATION THERAPIES
    Publication number: 20220395507
    Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SOS1 inhibitor and a KRas G12C inhibitor, pharmaceutical compositions comprising a such compositions, kits comprising such compositions and methods of use therefor.
    Type: Application
    Filed: May 24, 2022
    Publication date: December 15, 2022
    Inventors: Jacob Haling, John Michael Ketcham, Shilpi Khare