Patents by Inventor Jacob J. Bleesing

Jacob J. Bleesing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic assay for autoimmune lymphoproliferative syndrome (ALPS) and genetically related disorders
    Publication number: 20080090234
    Abstract: The methods and compositions of the invention find use in the clinical diagnosis of TNFRSF6-related syndromes, particularly autoimmune lymphoproliferative syndrome (ALPS). The compositions of the invention include isolated nucleic acid molecules and oligonucleotide pairs suitable for use in amplifying regions of the TNFRSF6 gene and in determining the nucleotide sequence of the TNFRSF6 gene in a patient. The invention facilitates efficient, cost-effective amplification of one or more regions of the TNFRSF6 gene. The nucleotide sequence of amplified DNA comprising one or more regions of the TNFRSF6 gene can be determined. Knowledge of the patient's nucleotide sequence in the TNFRSF6 gene allows diagnosis of the patient.
    Type: Application
    Filed: October 13, 2006
    Publication date: April 17, 2008
    Inventors: Kejian Zhang, Richard J. Wenstrup, Jacob J. Bleesing, Alexandra H. Filipovich