Patents by Inventor Jacob J. Chabon

Jacob J. Chabon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Systems for Analyzing Nucleic Acid Molecules
    Publication number: 20240105281
    Abstract: Processes and materials to detect cancer, transplant rejection, or fetal genetic abnormalities from a biopsy are described. In some cases, nucleic acid molecules, such as cell-free nucleic acids, can be sequenced, and the sequencing result can be utilized to detect sequences indicative of a neoplasm, transplant rejection, or fetal genetic abnormality. Detection of somatic variants occurring in phase and/or insertions and deletions (indels) can indicate the presence of cancer, transplant rejection, or fetal genetic abnormalities in a diagnostic scan, and a clinical intervention can be performed.
    Type: Application
    Filed: August 18, 2023
    Publication date: March 28, 2024
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jacob J. Chabon, David M. Kurtz, Maximilian Diehn, Arash Ash Alizadeh
  • Methods and systems for analyzing nucleic acid molecules
    Patent number: 11783912
    Abstract: Processes and materials to detect cancer, transplant rejection, or fetal genetic abnormalities from a biopsy are described. In some cases, nucleic acid molecules, such as cell-free nucleic acids, can be sequenced, and the sequencing result can be utilized to detect sequences indicative of a neoplasm, transplant rejection, or fetal genetic abnormality. Detection of somatic variants occurring in phase and/or insertions and deletions (indels) can indicate the presence of cancer, transplant rejection, or fetal genetic abnormalities in a diagnostic scan, and a clinical intervention can be performed.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: October 10, 2023
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jacob J. Chabon, David M. Kurtz, Maximilian Diehn, Arash Ash Alizadeh
  • Systems and Methods for Protecting Nucleic Acid Molecules
    Publication number: 20230242980
    Abstract: Processes and materials to protect nucleic acid molecules are described. Processes and materials to detect neoplasms from a biopsy are described. Processes and materials to build a sequencing library are described. Cell-free nucleic acids can be sequenced and the sequencing result can be utilized to detect sequences derived from a neoplasm.
    Type: Application
    Filed: August 24, 2022
    Publication date: August 3, 2023
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Maximilian Diehn, Arash Ash Alizadeh, Jacob J. Chabon, David M. Kurtz
  • Methods and Systems for Analyzing Nucleic Acid Molecules
    Publication number: 20220375540
    Abstract: Processes and materials to detect cancer, transplant rejection, or fetal genetic abnormalities from a biopsy are described. In some cases, nucleic acid molecules, such as cell-free nucleic acids, can be sequenced, and the sequencing result can be utilized to detect sequences indicative of a neoplasm, transplant rejection, or fetal genetic abnormality. Detection of somatic variants occurring in phase and/or insertions and deletions (indels) can indicate the presence of cancer, transplant rejection, or fetal genetic abnormalities in a diagnostic scan, and a clinical intervention can be performed.
    Type: Application
    Filed: April 27, 2022
    Publication date: November 24, 2022
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jacob J. Chabon, David M. Kurtz, Maximilian Diehn, Arash Ash Alizadeh