Patents by Inventor Jacob J. Utzig

Jacob J. Utzig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rebeccamycin derivative containing pharmaceutical composition
    Patent number: 4808613
    Abstract: There are disclosed analogs of the antitumor agent, rebaccamycin, which possess antineoplastic properties against mammalian, particularly experimental animal, tumor systems. The compounds of the invention are aminoalkylated derivatives of rebeccamycin produced by first reacting rebeccamycin with a strong base to obtain a reactive intermediate and then reacting the reactive intermediate with an aminoalkyl compound.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: February 28, 1989
    Assignee: Bristol-Myers Company
    Inventors: Takushi Kaneko, Henry S. Wong, Jacob J. Utzig
  • Rebeccamycin analogs
    Patent number: 4785085
    Abstract: There are disclosed analogs of the antitumor agent, rebeccamycin, which possess antineoplastic properties against mammalian, particularly experimental animal, tumor systems. The compounds of the invention are aminoalkylated derivatives of rebeccamycin produced by first reacting rebeccamycin with a strong base to obtain a reactive intermediate and then reacting the reactive intermediate with an aminoalkyl compound.
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: November 15, 1988
    Assignee: Bristol-Myers Company
    Inventors: Takushi Kaneko, Henry S. Wong, Jacob J. Utzig