Patents by Inventor Jacob L. Upperco

Jacob L. Upperco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12023459
    Abstract: Negative pressure therapy systems are provided for increasing urine production, the negative pressure therapy system including: (a) a pump assembly, the pump assembly including: (i) a pump configured to provide negative pressure to a kidney, and (ii) a controller configured to regulate the negative pressure provided by the pump within a pressure range that facilitates increased urine production from the kidney.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: July 2, 2024
    Assignee: Roivios Limited
    Inventors: John R. Erbey, II, Jacob L. Upperco, Michael Alan Fisher, Patrick William Strane, Lance Michael Black
  • Publication number: 20240207581
    Abstract: A ureteral catheter includes a drainage lumen including a proximal portion configured to be positioned in at least a portion of a patient's urethra and/or bladder and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including two or more openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen, wherein a number of the openings nearer to a distal end of the retention portion is greater than a number of the opening(s) nearer to a proximal end of the retention portion.
    Type: Application
    Filed: December 27, 2023
    Publication date: June 27, 2024
    Inventors: David E. Orr, Jacob L. Upperco, John R. Erbey, II
  • Patent number: 12011558
    Abstract: A pump assembly is provided, including a pump module configured to be positioned within an interior portion of a ureter and/or renal pelvis of a patient for providing negative pressure to the patient's ureter and/or kidney, the pump module including: a housing including a flow channel for conducting fluid, wherein the housing is configured to be positioned within the interior portion of the ureter and/the renal pelvis; and a pump element positioned within the channel to draw fluid through the channel; and a control module coupled to the pump module, the control module being configured to direct motion of the pump element to control flow rate of fluid passing through the channel, and including a housing configured to be positioned within at least one of a second interior portion of the patient's ureter, a second portion of the patient's renal pelvis, or an interior portion of a patient's bladder.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: June 18, 2024
    Assignee: Roivios Limited
    Inventors: David E. Orr, Jacob L. Upperco, John R. Erbey, II
  • Publication number: 20240091428
    Abstract: A negative pressure therapy device for inducing negative pressure in a urinary tract includes an inflow member and an outflow member. The inflow member includes (i) a proximal portion, (ii) a retention portion configured to be deployed within a renal pelvis of the urinary tract comprising a drainage hole leading to the inflow lumen, and (iii) an intermediate portion between the proximal portion and the retention portion. The intermediate portion is configured to extend through a portion of the kidney to the renal pelvis. The outflow member includes (i) a proximal portion, (ii) a distal end configured to be positioned in the ureter or bladder, and (iii) at least one intermediate portion extending from the proximal portion to the distal end.
    Type: Application
    Filed: September 14, 2023
    Publication date: March 21, 2024
    Inventors: John R. Erbey, Jacob L. Upperco, Bryan J. Tucker, Lance Michael Black
  • Patent number: 11918754
    Abstract: A ureteral catheter for placement in a kidney, renal pelvis, and/or in a ureter adjacent to the renal pelvis of a patient, includes: an elongated tube having a proximal end, a distal end, and a sidewall extending therebetween defining at least one drainage lumen extending through the tube, wherein a proximal portion of the elongated tube is essentially free of or free of openings; and an expandable retention portion which defines a three-dimensional shape positioned to maintain fluid flow from the kidney through at least the distal end of the tube and inhibit tissue of the ureter or renal pelvis from occluding the at least one drainage lumen at the distal end of the elongated tube upon application of negative pressure through the drainage lumen, wherein the three-dimensional space defined by the expandable retention portion encloses at least a portion of the distal end of the elongated tube.
    Type: Grant
    Filed: February 11, 2021
    Date of Patent: March 5, 2024
    Assignee: Roivios Limited
    Inventors: John R. Erbey, II, Jacob L. Upperco, David E. Orr
  • Patent number: 11904113
    Abstract: A ureteral catheter is provided, including a drainage lumen including a proximal portion and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including at least two openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen wherein a total area of a proximal most opening of the at least two openings is less than a total area of more distal opening(s) nearer to the distal end of the drainage lumen, and wherein when negative pressure is applied through the ureteral catheter, fluid is drawn into the ureteral catheter through the at least two openings.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: February 20, 2024
    Assignee: Roivios Limited
    Inventors: David E. Orr, Jacob L. Upperco, John R. Erbey, II
  • Patent number: 11904121
    Abstract: A negative pressure therapy system is provided for inducing negative pressure in a portion of a urinary tract of a patient, the system including: (a) at least one ureteral catheter configured to be positioned within a ureter and/or kidney of a patient; (b) one or more sensor(s) configured to determine information about urine produced within a urinary tract of the patient; and (c) a controller configured to increase urine production of the patient by adjusting one or more operating parameters of a negative pressure source for inducing negative pressure through the at least one ureteral catheter into the urinary tract of the patient, based at least in part upon the information determined by the one or more sensor(s).
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: February 20, 2024
    Assignee: Roivios Limited
    Inventors: John R. Erbey, II, Jacob L. Upperco, Michael Alan Fisher, Patrick William Strane, Lance Michael Black
  • Patent number: 11896785
    Abstract: A ureteral catheter includes a drainage lumen including a proximal portion configured to be positioned in at least a portion of a patient's urethra and/or bladder and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including two or more openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen, wherein a number of the openings nearer to a distal end of the retention portion is greater than a number of the opening(s) nearer to a proximal end of the retention portion.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: February 13, 2024
    Assignee: Roivios Limited
    Inventors: David E. Orr, Jacob L. Upperco, John R. Erbey, II
  • Patent number: 11819637
    Abstract: A ureteral catheter is provided, including a drainage lumen including a proximal portion and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including at least two openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen wherein a total area of a proximal most opening of the at least two openings is less than a total area of more distal opening(s) nearer to the distal end of the drainage lumen, and wherein when negative pressure is applied through the ureteral catheter, fluid is drawn into the ureteral catheter through the at least two openings.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: November 21, 2023
    Assignee: Roivios Limited
    Inventors: David E. Orr, Jacob L. Upperco, John R. Erbey, II
  • Publication number: 20230364322
    Abstract: A wearable garment for removing fluid from a urinary tract comprises a garment body configured to be worn by a patient; a pump provided on the garment body; and a reservoir provided on the garment body. The pump has a fluid inlet in fluid communication with a urinary catheter and a fluid outlet. The reservoir is provided in fluid communication with the outlet of the pump. The pump is configured to apply negative pressure to the urinary catheter to remove fluid from the urinary tract.
    Type: Application
    Filed: May 10, 2023
    Publication date: November 16, 2023
    Inventors: John R. Erbey, II, Jacob L. Upperco, Bryan J. Tucker, Lance Michael Black
  • Patent number: 11752300
    Abstract: A catheter includes an elongated tube having a distal portion having a distal end and a sidewall defining at least one drainage lumen. The catheter also includes a permeable material. The permeable material is configured to be deployed in the urinary tract to maintain the distal end of the elongated tube at a predetermined position in a bladder, a ureter, a renal pelvis, or a kidney of the patient. When deployed, the permeable material defines a three-dimensional shape of sufficient size to permit flow of at least a portion of fluid from the urinary tract through the permeable material and the at least one drainage lumen.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: September 12, 2023
    Assignee: Roivios Limited
    Inventors: John R. Erbey, II, Jacob L. Upperco, David E. Orr, Andrew Wilbourn, Daisy Smith, Colin Huber, Morgan Hinchey
  • Patent number: 11696999
    Abstract: A ureteral catheter is provided, including a drainage lumen including a proximal portion and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including at least two openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen wherein a total area of a proximal most opening of the at least two openings is less than a total area of more distal opening(s) nearer to the distal end of the drainage lumen, and wherein when negative pressure is applied through the ureteral catheter, fluid is drawn into the ureteral catheter through the at least two openings.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: July 11, 2023
    Assignee: Roivios Limited
    Inventors: David E. Orr, Jacob L. Upperco, John R. Erbey, II
  • Patent number: 11612714
    Abstract: Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: March 28, 2023
    Inventors: John R. Erbey, II, Jacob L. Upperco, David E. Orr, Michael Alan Fisher, Patrick William Strane, Lance Michael Black
  • Publication number: 20230068431
    Abstract: A system for removing fluid from a urinary tract includes: at least one sensor configured to detect signal(s) representative of bioelectrical impedance and communicate signal(s) representative of the impedance; and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the impedance is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the signal(s) representative of the impedance received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter when the impedance is below the predetermined value and to cease applying negative pressure when the impedance is at or above the predetermined value.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 2, 2023
    Inventors: John R. Erbey, II, Jacob L. Upperco, Bryan J. Tucker, Lance Michael Black
  • Publication number: 20230060814
    Abstract: A system for removing fluid from a urinary tract includes at least one sensor configured to detect signal(s) representative of pulmonary artery pressure and communicate signal(s) representative of the pulmonary artery pressure and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the pulmonary artery pressure is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the pulmonary artery pressure signal(s) received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter to remove fluid from a urinary tract when the pulmonary artery pressure is above the predetermined value and to cease applying negative pressure when the pulmonary artery pressure is at or below the predetermined value.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 2, 2023
    Inventors: John R. Erbey, II, Jacob L. Upperco, Bryan J. Tucker, Lance Michael Black
  • Patent number: 11541205
    Abstract: A coated urinary catheter or urinary stent device includes a urinary catheter or stent which, in a deployed position, includes or defines a protective surface area and a protected surface area and a coating upon at least a portion of the protective surface area. The coating includes a lubricant and an antimicrobial and/or pH buffering material. The device is configured such that, upon application of negative pressure to the catheter or stent, tissue of a urinary tract of a patient conforms or collapses onto the protective surface area and is thereby prevented or inhibited from occluding one or more protected drainage holes, ports or perforations of the catheter or stent.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: January 3, 2023
    Inventors: John R. Erbey, II, Bryan J. Tucker, Jacob L. Upperco
  • Patent number: 11511075
    Abstract: A coated urinary catheter or urinary stent device includes a urinary catheter or stent which, in a deployed position, includes or defines a protective surface area and a protected surface area and a coating upon at least a portion of the protective surface area. The coating includes a lubricant and an antimicrobial and/or pH buffering material. The device is configured such that, upon application of negative pressure to the catheter or stent, tissue of a urinary tract of a patient conforms or collapses onto the protective surface area and is thereby prevented or inhibited from occluding one or more protected drainage holes, ports or perforations of the catheter or stent.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: November 29, 2022
    Inventors: John R. Erbey, II, Bryan J. Tucker, Jacob L. Upperco
  • Publication number: 20220362515
    Abstract: A percutaneous urinary catheter configured to be deployed in a urinary tract, including: (a) a proximal portion; and (b) a distal portion including a retention portion configured to be deployed in a kidney and/or a renal pelvis, the retention portion including one or more drainage holes leading to one or more lumen(s) within the proximal portion, wherein the retention portion, when deployed, defines a three-dimensional shape sized and positioned to maintain patency of fluid flow between the kidney and/or renal pelvis and a proximal end of the catheter by inhibiting mucosal tissue from appreciably occluding the one or more drainage holes when negative pressure is applied through the catheter.
    Type: Application
    Filed: July 21, 2022
    Publication date: November 17, 2022
    Inventors: John R. Erbey, II, Bryan J. Tucker, Jacob L. Upperco
  • Patent number: 11478607
    Abstract: Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: October 25, 2022
    Inventors: John R. Erbey, II, Jacob L. Upperco, David E. Orr, Michael Alan Fisher, Patrick William Strane, Lance Michael Black
  • Patent number: 11471583
    Abstract: A method for removing excess fluid from a patient with hemodilution is provided. The method includes: deploying a urinary tract catheter into the patient such that flow of urine from the ureter and/or kidney is transported within a drainage lumen of the catheter; applying negative pressure to the ureter and/or kidney through the drainage lumen of the catheter to extract urine from the patient; periodically measuring a hematocrit value of the patient; and if the measured hematocrit value is greater than a predetermined threshold value, ceasing the application of the negative pressure to the ureter and/or kidney. A system for removing excess fluid from a patient with hemodilution including a ureteral catheter and a pump is also provided.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: October 18, 2022
    Inventors: John R. Erbey, II, Jacob L. Upperco, Michael Alan Fisher, Patrick William Strane, Lance Michael Black, David E. Orr