Patents by Inventor Jacob Lilly

Jacob Lilly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12643134
    Abstract: Apparatus, systems (including solvent or enzyme), and methods of degrading plastic are described. Plastic waste is stretched in the presence of solvent. The surface may be further treated to increase hydrophilicity. The resulting plastics can be treated with plastic-degrading enzyme either with microorganisms or direct application of enzyme.
    Type: Grant
    Filed: May 24, 2022
    Date of Patent: June 2, 2026
    Assignee: Battelle Memorial Institute
    Inventors: Amy M. Heintz, Jacob Lilly, Christopher Buurma, Ryan W. Daly, John Bartholomew
  • Publication number: 20260139281
    Abstract: The invention provides a method and system for the enzymatic transesterification of fatty acids or fatty acid derived products to produce lubricant esters. The process involves a reaction mixture containing a fatty acid or fatty acid-derived substrate, an alcohol and a lipolytic enzyme catalyst. A reactive column with a porous frit is employed through which air is bubbled into a mixture of fatty acid derivatives, alcohol and an immobilized lipase catalyst. The air bubbles promote mixing and the subsequent stripping of volatile by-products, thereby increasing ester formation. This process can be carried out at ambient temperature, without the need for external heating or microwave irradiation. The method achieves greater that 99 mol % conversion to ester products at lower energy when compared to conventional thermochemical transesterification.
    Type: Application
    Filed: November 20, 2025
    Publication date: May 21, 2026
    Inventors: Daniel B. Garbark, Jeffrey T. Cafmeyer, Jacob Lilly
  • Publication number: 20260014186
    Abstract: The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
    Type: Application
    Filed: September 17, 2025
    Publication date: January 15, 2026
    Inventors: Anthony D. DUONG, Cherry GUPTA, Kenneth R. SIMS, JR., Danielle HUK, Jacob LILLY, Stephanie M. KUTE, Mike KOERIS
  • Publication number: 20250333573
    Abstract: Methods for deconstructing polyester-cotton blended textile waste and biodegradable polyester packaging waste using microbial cells for the fermentative production of polyhydroxybutyrate (PHB), novel engineered Halomonas strains, and use of these strains in PHB production. An engineered microbial cell and compositions comprising PHB are also described.
    Type: Application
    Filed: January 27, 2025
    Publication date: October 30, 2025
    Inventors: Jacob Lilly, William R. Henson, Albert J. Darling
  • Patent number: 12433910
    Abstract: The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
    Type: Grant
    Filed: August 27, 2024
    Date of Patent: October 7, 2025
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Anthony D. Duong, Cherry Gupta, Kenneth R. Sims, Jr., Danielle Huk, Jacob Lilly, Stephanie M. Kute, Mike Koeris
  • Publication number: 20240415865
    Abstract: The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
    Type: Application
    Filed: August 27, 2024
    Publication date: December 19, 2024
    Inventors: Anthony D. DUONG, Cherry GUPTA, Kenneth R. SIMS, Jr., Danielle HUK, Jacob LILLY, Stephanie M. KUTE, Mike KOERIS
  • Patent number: 12109223
    Abstract: The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
    Type: Grant
    Filed: February 16, 2024
    Date of Patent: October 8, 2024
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Anthony D. Duong, Cherry Gupta, Kenneth R. Sims, Jr., Danielle Huk, Jacob Lilly, Stephanie M. Kute, Mike Koeris
  • Publication number: 20240253096
    Abstract: Apparatus, systems (including solvent or enzyme), and methods of degrading plastic are described. Plastic waste is stretched in the presence of solvent. The surface may be further treated to increase hydrophilicity. The resulting plastics can be treated with plastic-degrading enzyme either with microorganisms or direct application of enzyme.
    Type: Application
    Filed: May 24, 2022
    Publication date: August 1, 2024
    Inventors: Amy M. Heintz, Jacob Lilly, Christopher Buurma, Ryan W. Daly
  • Publication number: 20240189338
    Abstract: The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
    Type: Application
    Filed: February 16, 2024
    Publication date: June 13, 2024
    Inventors: Anthony D. DUONG, Cherry GUPTA, Kenneth R. SIMS, Danielle HUK, Jacob LILLY, Stephanie M. KUTE, Mike KOERIS
  • Publication number: 20240018331
    Abstract: The present invention is directed to polyamide recovery from domestic or commercial waste. In particular, a method of polyamide recovery from domestic or commercial waste, via a selective dissolution procedure, using a methanol-calcium chloride solvent system, that isolates and recovers the polyamide at a particle size range that is particularly suitable for enzymatic depolymerization.
    Type: Application
    Filed: July 6, 2023
    Publication date: January 18, 2024
    Inventors: Matthew COLACHIS, Jacob LILLY, Edward TRIGG, Kate KUCHARZYK, Amy Marie Heintz, Megan MOORE
  • Publication number: 20220175812
    Abstract: The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.
    Type: Application
    Filed: December 3, 2021
    Publication date: June 9, 2022
    Inventors: Anthony D. DUONG, Cherry GUPTA, Kenneth R. SIMS, JR., Danielle HUK, Jacob LILLY, Stephanie M. KUTE, Mike KOERIS
  • Patent number: 11305106
    Abstract: The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: April 19, 2022
    Assignee: Battelle Memorial Institute
    Inventors: Amy M. Heintz, Krenar Shqau, Ramanathan Lalgudi, Patrick Ganzer, Mingming Zhang, Jacob Lilly
  • Publication number: 20220080187
    Abstract: The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
    Type: Application
    Filed: November 23, 2021
    Publication date: March 17, 2022
    Inventors: Amy M. Heintz, Krenar Shqau, Ramanathan Lalgudi, Patrick Ganzer, Mingming Zhang, Jacob Lilly
  • Publication number: 20210350877
    Abstract: A point of care device, comprises a chamber configured to contain a swab. Once a swab is loaded, the device introduces a buffer into the chamber, then lyses cells collected by the swab. Probes such as padlock probes target a specified content such as a virus (e.g., SARS-CoV-2 RNA) and will bind, splint ligate, and rapidly isothermally amplify (e.g., using rolling circle amplification). Also described is a wastewater pathogen tracking dashboard and schema for detecting and tracking pathogen spread within communities by monitoring microbial and viral RNA.
    Type: Application
    Filed: May 6, 2021
    Publication date: November 11, 2021
    Inventors: Rachel R. Spurbeck, Christopher Johnson, Jacob Lilly, Jared M. Schuetter, Patrick H. Wilson
  • Publication number: 20200214564
    Abstract: The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
    Type: Application
    Filed: October 9, 2019
    Publication date: July 9, 2020
    Inventors: Amy M. Heintz, Krenar Shqau, Ramanathan Lalgudi, Patrick Ganzer, Ming Ming Zhang, Jacob Lilly