Abstract: The disclosure describes a BHA that generates electricity downhole which can then be utilized with an electric motor to turn the drive shaft and for drive shaft orientation. The disclosure also describes a more accurate MWD measurements by placing MWD sensors closer to drill bit.

Abstract: A CO2 based system, such as a heat pump system or a refrigeration system, is disclosed. The system comprises a plurality of ejectors arranged in parallel. Each of the ejectors comprises a motive port and a suction port. Each of the ejectors has a fixed geometry. A first actuated ball valve is arranged in front of the motive port. A second actuated ball valve is arranged in front of the suction port. The system comprises a control unit arranged and configured to control the activity of the ball valves on the basis of one or more predefined criteria.

Abstract: The present invention provides ISVD polypeptide derivatives capable of binding coagulation Factor IX(a) and Factor X(a) which are highly potent and provide a sufficiently long half-life such to allow for effective subcutaneous—as well as peroral administration. The ISVD polypeptides derivatives disclosed herein are thus suitable for treatment of haemophilia A, haemophilia A with inhibitors and acquired haemophilia A by various routes of administration including subcutaneous and peroral administration.

Abstract: The application relates to unique FX binding molecules, such as antibodies and fragments thereof which are useful in the treatment of haemophilia.

Abstract: Implementations described and claimed herein provide apparatus and techniques for providing a seal for a polished rod. One example apparatus is a stuffing box. The stuffing box generally includes: a first flange configured to surround a polished rod; a second flange configured to surround the polished rod; a seal package disposed between the first flange and the second flang, the seal package being configured to surround and connect to the polished rod; and a flexible membrane surrounding the seal package, the flexible membrane being connected to at least a portion of the seal package.

Abstract: The application relates to unique FX binding molecules, such as antibodies and fragments thereof which are useful in the treatment of haemophilia.

Abstract: A drill string system includes a drill bit disposed at a distal end of a drill string. A clutch is coupled with the drill bit. A mud motor is coupled to the clutch, and the mud motor is operable to receive a drilling fluid therein and transfer torque to the drill bit through the clutch. The clutch disengages upon application of a torque exceeding a predetermined threshold.

Abstract: A drill string system includes a drill bit disposed at a distal end of a drill string. A clutch is coupled with the drill bit. A mud motor is coupled to the clutch, and the mud motor is operable to receive a drilling fluid therein and transfer torque to the drill bit through the clutch. The clutch disengages upon application of a torque exceeding a predetermined threshold.

Abstract: The application relates to unique FX binding molecules, such as antibodies and fragments thereof which are useful in the treatment of haemophilia.

Abstract: A removable vena cava filter configured for reduced trauma and enhanced visualization of anchoring hook placement relative to the vessel wall is disclosed. The filter includes a plurality of struts, each having an anchoring hook and a stop member proximate the anchoring hook. The stop members are configured to engage the vessel wall to prevent excessive penetration of the anchoring hooks into the vessel wall and to aid in the identification of anchoring hook placement relative to the vessel wall.

Abstract: An occlusion device (30) includes at least one self-expanding frame (42, 44) and graft material (46). Occlusion occurs by constricting the graft material (46) at a substantially central point or at an end of the device. The constriction is sized such that a guide wire (34) is able to pass therethrough. A valve mechanism (50) includes a screen (52) made from a resilient material and which includes a closable opening (54). The valve mechanism (50) allows a guide wire to pass through the occlusion device (30) while an effective physical barrier is maintained after removal of the guide wire (34).

Abstract: A removable vena cava filter configured for reduced trauma and enhanced visualization of anchoring hook placement relative to the vessel wall is disclosed. The filter includes a plurality of struts, each having an anchoring hook and a stop member proximate the anchoring hook. The stop members are configured to engage the vessel wall to prevent excessive penetration of the anchoring hooks into the vessel wall and to aid in the identification of anchoring hook placement relative to the vessel wall.

Abstract: A removable vena cava filter configured for reduced trauma and enhanced visualization of anchoring hook placement relative to the vessel wall is disclosed. The filter includes a plurality of struts, each having an anchoring hook and a stop member proximate the anchoring hook. The stop members are configured to engage the vessel wall to prevent excessive penetration of the anchoring hooks into the vessel wall and to aid in the identification of anchoring hook placement relative to the vessel wall.

Abstract: A medical device for collecting objects from a body lumen comprises a catheter, a basket having a closed first end and an open second end, and an actuator connected to the closed first end of the basket, the catheter and basket moveable relative to one another between a first configuration and a second configuration to draw objects from a body lumen into the basket. In the first configuration the closed first end of the basket is inside the catheter and the open second end is everted over at least a part of the closed first end. The apparatus may be actuated to pull the closed first end of the basket further into the catheter and invert the second end of the basket, the second end scraping the sides of the lumen as it inverts, surrounding an object in the lumen, and drawing the object into the basket.

Abstract: An occlusion device (10) includes a cannula (24), a dilator tip (20) fixed to the cannula and a frame member formed of an occlusion member (28) and a sleeve (30). The occlusion member (28) is covered with occlusion material (26). The cannula (24) is in the form of a tube having a lumen (25) passing therethrough. The dilator tip (20) also has a lumen therethrough and a valve (32). The arrangement is such that the occluder (10) can be delivered by an over the wire method using a guide wire, whereupon the cannula and dilator tip remain in the patient as part of the occluder assembly (10).

Abstract: A filter device for trapping embolic debris comprises a bag which is deployed by everting it from an end of a delivery catheter. After release from the catheter, with the assistance of a pusher member, the open end of the bag self-expands against the walls of a body lumen. In one method of removal after use, the device is withdrawn into catheter by pulling on a wire attached to the closed end of the bag.

Abstract: A removable vena cava filter (10) configured for reduced trauma and enhanced visualization of anchoring hook placement relative to the vessel wall is disclosed. The filter includes a plurality of struts (12a-d), each having an anchoring hook (26) and a stop member (24) proximate the anchoring hook. The stop members are configured to engage the vessel wall to prevent excessive penetration of the anchoring hooks into the vessel wall and to aid in the identification of anchoring hook placement relative to the vessel wall.

Abstract: A removable vena cava filter configured for reduced trauma and enhanced visualization of anchoring hook placement relative to the vessel wall is disclosed. The filter includes a plurality of struts, each having an anchoring hook and a stop member proximate the anchoring hook. The stop members are configured to engage the vessel wall to prevent excessive penetration of the anchoring hooks into the vessel wall and to aid in the identification of anchoring hook placement relative to the vessel wall.

Abstract: A medical device for collecting objects from a body lumen comprises a catheter, a basket having a closed first end and an open second end, and an actuator connected to the closed first end of the basket, the catheter and basket moveable relative to one another between a first configuration and a second configuration to draw objects from a body lumen into the basket. In the first configuration the closed first end of the basket is inside the catheter and the open second end is everted over at least a part of the closed first end. The apparatus may be actuated to pull the closed first end of the basket further into the catheter and invert the second end of the basket, the second end scraping the sides of the lumen as it inverts, surrounding an object in the lumen, and drawing the object into the basket.

Abstract: An introducer for use in the implantation and retrieval of a device in a patient includes a catheter (43) within which a stylet (14) is slidably carried, the stylet (14) being biased to a retracted position by a spring (35) and deployable by depression of an actuator (50). A locking device (40) locks the stylet (14) relative to the catheter (43) such that the locking device (40) must be disengaged prior to operation of the actuator (50). In the preferred embodiment, both the locking device (40) and the actuator (50) must be actuated by movement thereof in a direction substantially perpendicular to the direction of motion of the stylet (14). In an alternative embodiment, it is the catheter (43) which moves relative to the stylet (14).