Patents by Inventor Jacob N. Wohlstadter

Jacob N. Wohlstadter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8770471
    Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such information in the conduct of an assay by an assay system.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: July 8, 2014
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Xinri Cong, Jerome Jackson, Carl Stevens, Michael Vock, Jacob N. Wohlstadter
  • Patent number: 8722323
    Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: May 13, 2014
    Assignee: Meso Scale Technologies LLP
    Inventors: Jacob N. Wohlstadter, James L. Wilbur, George B. Sigal, Mark T. Martin, Liang-Hong Guo, Alan Fischer, Jon Leland, Mark A. Billadeau, Larry R. Helms, Ramin Darvari
  • Patent number: 8541174
    Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: September 24, 2013
    Assignee: Meso Scale Technologies, LLC
    Inventors: Jacob N. Wohlstadter, James L. Wilbur, George B. Sigal, Mark T. Martin, Liang-Hong Guo, Alan Fischer, Jon Leland, Mark A. Billadeau
  • Publication number: 20120190591
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: April 4, 2012
    Publication date: July 26, 2012
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20120190590
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: April 4, 2012
    Publication date: July 26, 2012
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20120145778
    Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such information in the conduct of an assay by an assay system.
    Type: Application
    Filed: July 26, 2011
    Publication date: June 14, 2012
    Applicant: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Xinri Cong, Jerome Jackson, Carl Stevens, Michael Vock, Jacob N. Wohlstadter
  • Publication number: 20110220777
    Abstract: We describe a detection module useful with an apparatus and/or system for conducting luminescence assays.
    Type: Application
    Filed: March 8, 2011
    Publication date: September 15, 2011
    Applicant: Meso Scale Technologies, LLC
    Inventors: Charles M. Clinton, Jacob N. Wohlstadter
  • Publication number: 20110203924
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: November 11, 2010
    Publication date: August 25, 2011
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Publication number: 20110105354
    Abstract: Multiplexed test measurements are conducted using an assay module having a plurality of assay domains. In preferred embodiments, these measurements are conducted in assay modules having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: December 23, 2010
    Publication date: May 5, 2011
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Eli N. Glezer, Kent Johnson, Michael Tsionsky, John H. Kenten, Jeff D. Debad, Robert M. Umek, Paula Denney Eason, Hans Biebuyck, Jacob N. Wohlstadter, James Wilbur, George Sigal, Niranjan Y. Sardesai
  • Publication number: 20110059870
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Application
    Filed: November 11, 2010
    Publication date: March 10, 2011
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 7858321
    Abstract: Multiplexed test measurements are conducted using an assay module having a plurality of assay domains. In preferred embodiments, these measurements are conducted in assay modules having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: December 28, 2010
    Assignee: Meso Scale Technologies, LLC
    Inventors: Eli N. Glezer, Kent Johnson, Michael Tsionsky, John H. Kenten, Jeff D. Debad, Robert M. Umek, Paula Denney Eason, Hans Biebuyck, Jacob N. Wohlstadter, James Wilbur, George Sigal, Niranjan Y. Sardesai
  • Patent number: 7842246
    Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: November 30, 2010
    Assignee: Meso Scale Technologies, LLC
    Inventors: Jacob N. Wohlstadter, Eli Glezer, James Wilbur, George Sigal, Kent Johnson, Charles Clinton, Alan Kishbaugh, Bandele Jeffrey-Coker, Jeff D. Debad, Alan B. Fischer
  • Patent number: 7824925
    Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: November 2, 2010
    Assignee: Meso Scale Technology LLP
    Inventors: Jacob N. Wohlstadter, James Wilbur, George Sigal, Mark Martin, Liang-Hong Guo, Alan Fischer, Jon Leland, Mark A. Billadeau, Larry R. Helms, Ramin Darvari
  • Publication number: 20100140086
    Abstract: A method and apparatus for performing electrochemiluminescence assays are presented. In exemplary embodiments of the present invention an apparatus comprises an ECL-inactive electrode surface having a first assay-ligand immobilized thereon and an ECL-active microparticle having a second assay ligand immobilized thereon. In exemplary embodiments of the present invention a method comprises (a) forming a mixture comprising an electrochemiluminescent label and a microparticle having a first assay-ligand immobilized thereon, (b) applying electrochemical energy to an electrode surface in the presence of said mixture, and (c) measuring emitted electrochemiluminescence, where the microparticle is ECL-active and where the electrode surface is ECL-inactive when electrochemical energy is applied to it in the presence of said mixture.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 10, 2010
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: George B. Sigal, Jacob N. Wohlstadter, Satyanarayana Gudibande, Mark T. Martin, James L. Wilbur
  • Patent number: 7682788
    Abstract: A method and apparatus for performing electrochemiluminescence assays are presented. In exemplary embodiments of the present invention an apparatus comprises an ECL-inactive electrode surface having a first assay-ligand immobilized thereon and an ECL-active microparticle having a second assay ligand immobilized thereon. In exemplary embodiments of the present invention a method comprises (a) forming a mixture comprising an electrochemiluminescent label and a microparticle having a first assay-ligand immobilized thereon, (b) applying electrochemical energy to an electrode surface in the presence of said mixture, and (c) measuring emitted electrochemiluminescence, where the microparticle is ECL-active and where the electrode surface is ECL-inactive when electrochemical energy is applied to it in the presence of said mixture.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: March 23, 2010
    Assignee: Meso Scale Technologies, LLC
    Inventors: George B. Sigal, Jacob N. Wohlstadter, Satyanarayana Gudibande, Mark T. Martin, James L. Wilbur
  • Patent number: 7167313
    Abstract: Recent advances in surface techniques have lead to the development of extremely small (sub-micron) scale features. These techniques allow the formation of polymer micro-lenses as well as variable focus liquid lenses. The present invention primarily concerns the use of small scale lenses for the fabrication of novel displays which exhibit three-dimensional (3D) effects. Both still images and video images (or other motion images) can be generated.
    Type: Grant
    Filed: June 20, 2005
    Date of Patent: January 23, 2007
    Inventor: Jacob N. Wohlstadter
  • Patent number: 7015046
    Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: March 21, 2006
    Assignee: MesoScale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, James Wilbur, George Sigal, Mark Martin, Liang-Hong Guo, Alan Fischer, Jon Leland, Mark A. Billadeau, Larry R. Helms, Ramin Darvari
  • Patent number: 7008796
    Abstract: An assay apparatus includes a cell with a working electrode and a sonicating device structurally coupled to the cell for sonication the contents of the cell.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: March 7, 2006
    Assignee: MesoScale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, James Wilbur, George Sigal, Mark Martin, Alan Fischer, Larry R. Helms, Ramin Darvari
  • Patent number: D516221
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: February 28, 2006
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Eli N. Glezer, Charles Clinton, Brian A. Self, John Mattson, Lance Hussey, Nasahn Sheppard, Hirotomi Teranishi, Ravi Sawhney
  • Patent number: D705437
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: May 20, 2014
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Ian Chamberlin, Charles M. Clinton, Eli N. Glezer, Manish Kochar, Sandor Kovacs, Aaron Leimkuehler, Rodger Darin Osborne, Jacob N. Wohlstadter