Abstract: Methods and apparatus are provided for measurement and analysis of patient anatomy with an ultrasound imaging system which generates an ultrasound image of a region of a patient and provides coordinates of walls of vessels in the image. In response to placement of a cursor within the vessel in the ultrasound image, one or more parameters of the vessel in the vicinity of the cursor are determined automatically from the wall coordinates. The determined parameter values are recorded. The vessel parameters may include vessel diameter, vessel center coordinates and/or vessel wall directions. The vessel may be automatically mapped by moving the cursor to multiple positions along the vessel and determining the parameters of interest at each cursor position. The smallest vessel diameter may be determined and highlighted in the ultrasound image.