Patents by Inventor Jacob Valiyaveettil

Jacob Valiyaveettil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazolopyridazine compounds, use as inhibitors of the kinase LRRK2, and methods for preparation thereof
    Patent number: 9187484
    Abstract: Provided are novel LRRK2 kinase inhibitors and methods of treating disease states using these inhibitors. Examples of LRRK2 kinase inhibitors are compounds of the formula: or derivatives thereof. An example is 1-(piperidin-1-yl)-2-((3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butan-1-one. Particular uses include treating neurodegenerative diseases, cancer, autoimmune diseases and leprosy.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: November 17, 2015
    Assignees: Southern Research Institute, The UAB Research Foundation
    Inventors: Robert A. Galemmo, Jr., Andrew B. West, Joseph A. Maddry, Subramaniam Ananthan, Ashish Kumar Pathak, Jacob Valiyaveettil
  • TRIAZOLOPYRIDAZINE COMPOUNDS, USE AS INHIBITORS OF THE KINASE LRRK2, AND METHODS FOR PREPARATION THEREOF
    Publication number: 20130296298
    Abstract: The present invention provides novel LRRK2 kinase inhibitors and methods of treating disease states using these inhibitors.
    Type: Application
    Filed: May 2, 2013
    Publication date: November 7, 2013
    Applicants: THE UAB RESEARCH FOUNDATION, Southern Research Institute
    Inventors: Robert A. Galemmo, JR., Andrew B. West, Joseph A. Maddry, Subramaniam Ananthan, Ashish Kumar Pathak, Jacob Valiyaveettil