Patents by Inventor Jacob Vaya

Jacob Vaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230202967
    Abstract: The present invention relates to lyso-diacylglyceryltrimethylhomoserine (lyso- DGTS) or derivatives thereof for use in the treatment of atherosclerotic cardiovascular disease, and further provides particular such lyso-DGTS derivatives.
    Type: Application
    Filed: February 20, 2023
    Publication date: June 29, 2023
    Applicant: GAVISH-GALILEE BIO APPLICATIONS LTD.
    Inventors: Jacob VAYA, Soliman KHATIB, Emma KVITNITSKY
  • Patent number: 11591288
    Abstract: The present invention relates to lyso-diacylglyceryltrimethylhomoserine (lyso-DGTS) or derivatives thereof for use in the treatment of atherosclerotic cardiovascular disease, and further provides particular such lyso-DGTS derivatives.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: February 28, 2023
    Assignee: GAVISH-GALILEE BIO APPLICATIONS LTD.
    Inventors: Jacob Vaya, Soliman Khatib, Emma Kvitnitsky
  • Publication number: 20210023217
    Abstract: A protein, e.g. an antibody, coated with a non-immunogenic molecule selected from an amino-monosaccharide-biotin adduct or a monosaccharide-biotin adduct is disclosed, wherein the coated protein, which has diminished immunogenicity relative to the uncoated protein and intact biological activity, enables, for example, cross-species vaccination.
    Type: Application
    Filed: October 11, 2020
    Publication date: January 28, 2021
    Inventors: Jacob PITCOVSKI, Jacob VAYA, Soliman KHATIB, Elina AIZENSHTEIN, Tal GEFEN
  • Patent number: 10821179
    Abstract: A protein, e.g. an antibody, coated with a non-immunogenic molecule selected from an amino-monosaccharide-biotin adduct or a monosaccharide-biotin adduct is disclosed, wherein the coated protein, which has diminished immunogenicity relative to the uncoated protein and intact biological activity, enables, for example, cross-species vaccination.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: November 3, 2020
    Assignee: GAVISH-GALILEE BIO APPLICATIONS, LTD.
    Inventors: Jacob Pitcovski, Jacob Vaya, Soliman Khatib, Elina Aizenshtein, Tal Gefen
  • Publication number: 20200308100
    Abstract: The present invention relates to lyso-diacylglyceryltrimethylhomoserine (lyso-DGTS) or derivatives thereof for use in the treatment of atherosclerotic cardiovascular disease, and further provides particular such lyso-DGTS derivatives.
    Type: Application
    Filed: August 22, 2018
    Publication date: October 1, 2020
    Inventors: Jacob VAYA, Soliman KHATIB, Emma KVITNITSKY
  • Publication number: 20160120977
    Abstract: A protein, e.g. an antibody, coated with a non-immunogenic molecule selected from an amino-monosaccharide-biotin adduct or a monosaccharide-biotin adduct is disclosed, wherein the coated protein, which has diminished immunogenicity relative to the uncoated protein and intact biological activity, enables, for example, cross-species vaccination.
    Type: Application
    Filed: November 4, 2015
    Publication date: May 5, 2016
    Applicant: GAVISH-GALILEE BIO APPLICATIONS, LTD.
    Inventors: Jacob Pitcovski, Jacob Vaya, Soliman Khatib, Elina Aizenshtein, Tal Gefen
  • Publication number: 20120156227
    Abstract: A protein covalently linked to, or coated with, a non-immunogenic molecule selected from an amino monosaccharide-biotin adduct or a monosaccharide-biotin adduct is disclosed, wherein the coated protein, which has diminished immuno-genicity relative to the uncoated protein and intact biological activity, enables, for example, cross-species vaccination
    Type: Application
    Filed: June 6, 2010
    Publication date: June 21, 2012
    Applicant: GAVISH-GALILEE BIO APPLICATIONS LTD.
    Inventors: Jacob Pitcovski, Jacob Vaya, Soliman Khatib, Alina Aizenshtein, Tal Gefen
  • Publication number: 20080311667
    Abstract: The invention provides oxogenous markers, designed and synthesized for the measurement and characterization of oxidative/nitrosative stress levels, thus enable the identification of the type of reactive ROS/NRS involved, characterization of the damaged products and their formation kinetics, and thereby the identification of pathological conditions associated with oxidative/nitrosative stress, before appearing or at the stage of development.
    Type: Application
    Filed: March 30, 2006
    Publication date: December 18, 2008
    Inventors: Jacob Vaya, Snait Tamir
  • Publication number: 20080108129
    Abstract: Methods for obtaining modified proteins or virus with an intact native binding site and decreased antigenicity and modified proteins or virus obtainable by said methods are provided. The methods of protein or virus modification comprise masking with non-immunogenic molecules the protein or the virus surface, except for the protein or the virus binding site. Examples of modified proteins or virus that can be modified in accordance to the methods include polyclonal or monoclonal antibodies, modified replication-defective virus, hormones, and enterotoxins.
    Type: Application
    Filed: December 29, 2005
    Publication date: May 8, 2008
    Applicant: Gavish-Galillee Bio Applications Ltd.
    Inventors: Jacob Pitcovski, Jacob Vaya
  • Patent number: 4889929
    Abstract: Process for the preparation of 1'-ethoxy carbonyloxy ethyl esters of penicillins, wherein a compound of the formula ##STR1## in which A is phenyl, phenoxy or 4-hydroxyphenyl, B is hydrogen, an amino group or a protected amino group and Z is hydrogen or a cation selected from the group of alkali metal, tri (lower alkyl ) ammonium and tetra (lower alkyl) ammonium, is reacted with 1-bromoethyl ethyl carbonate in an organic solvent and when B is a protected amino group the protecting group is split off to yield a primary amino group.There are also provided novel compounds of the formula ##STR2## in which Ph is phenyl and R is CH.sub.3 -- or C.sub.2 H.sub.5 --.
    Type: Grant
    Filed: March 26, 1987
    Date of Patent: December 26, 1989
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Jacob Vaya, David Ladkani, Clara Schoenberger, Joseph Kaspi, Gad Salemnick, Haim Yellin, Stephan Cherkez
  • Patent number: 4472312
    Abstract: Regio- and stereospecific method for the preparation of daunomycinone and derivatives thereof utilizing the p-nitrobenzyloxy carbonyl group as a blocking group.
    Type: Grant
    Filed: August 1, 1983
    Date of Patent: September 18, 1984
    Assignee: Research Corporation
    Inventors: Lakshminarayan Anathasubramanian, T. Ross Kelly, Jacob Vaya
  • Patent number: 4415498
    Abstract: Regio- and stereospecific method for the preparation of daunomycinone and derivatives thereof utilizing the p-nitrobenzyloxy carbonyl group as a blocking group.
    Type: Grant
    Filed: November 7, 1979
    Date of Patent: November 15, 1983
    Assignee: Research Corporation
    Inventors: Lakshminarayan Anathasubramanian, T. Ross Kelly, Jacob Vaya