Abstract: A portable container has a payload chamber for holding medicines, vaccines, biological samples or other medical goods and a lid operable to access the payload chamber. The portable container also has an electronic system with one or more power storage devices, circuitry that wirelessly communicates via a cell radio with a cloud-based data storage system or a remote electronic device, and an electronic display screen. The electronic system can a) automatically switch sender and recipient information on the electronic display screen to facilitate return of the portable container to the sender or b) automatically contact a parcel carrier to alert the parcel carrier that the portable container is ready for pickup.

Abstract: Glucose-sensing luminescent dyes, polymers, and sensors are provided. Additionally, systems including the sensors and methods of using these sensors and systems are provided.

Abstract: A portable cooler container system is described. The cooler container system includes a container body having a payload chamber and a temperature control system including a thermoelectric element, a hot side heat sink a cold side heat sink and a pump. The portable cooler container system further includes a conduit in thermal communication with a thermal mass, sensors, power storage elements and circuitry to control operation of the temperature control system.

Abstract: A portable container has a payload chamber for holding medicines, vaccines, biological samples or other medical goods and a lid operable to access the payload chamber. The portable container also has an electronic system with one or more power storage devices, circuitry that wirelessly communicates via a cell radio with a cloud-based data storage system or a remote electronic device, and an electronic display screen. The electronic system can a) automatically switch sender and recipient information on the electronic display screen to facilitate return of the portable container to the sender or b) automatically contact a parcel carrier to alert the parcel carrier that the portable container is ready for pickup.

Abstract: Garments or footwear with active temperature control include one or more heating or cooling elements, one or more batteries, and one or more power receivers. Circuitry of the garment of footwear is configured to control the delivery of power to the one or more heating or cooling elements to heat or cool one or more portions of the garment associated with the one or more heating or cooling elements.

Abstract: A method, a system and computer program product for controlling exposure of a substrate positioned on a platen in an ion implantation system to an ion beam. A first current value determined based on a powering potential powering an ion source is received. A second current value determined based on an accelerating potential or a decelerating potential supplied to the ion implantation apparatus and affecting generation of the ion beam by the ion source for application to a substrate positioned on a platen is received. One or more energy filter supply current values are determined based on one or more energy filter supply potentials supplied to an energy filter positioned in the path of the ion beam. Platen position values are generated based on the first and second current values and energy filter supply current values. A position of the platen is adjusted using platen position values.

Abstract: A portable cooler container includes a container body with a payload chamber. The container body has an insulated vessel and a temperature control system that cools the payload chamber.

Abstract: A portable cryogenic cooler container is provided, with a payload chamber for one or more temperature sensitive or perishable goods. A cooling unit is disposed in the payload chamber. The cooling unit includes a vessel filled with a cooling material (e.g., liquid nitrogen) and closed with a lid. One or more apertures of the cooling unit are operable to allow a chilled gas (e.g., gaseous nitrogen) to be vented without pressure build up in the cooler.

Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A, X, R1-R9, R12 and R13 are as described herein (I). Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: A cooler container kit is described. The cooler container kit includes a container body having a payload chamber, a lid, an electronic system, and one or more electrical connectors. The cooler kit further includes a conduit extending about the payload chamber. The cooler container kit further includes a temperature control system including a cold side heat sink, hot side heat sink, thermoelectric module, and a pump operable to flow a liquid relative to the cold side heat sink to cool the liquid. The cooler container kit further includes a docking unit.

Abstract: A lighting assembly and method generate a three-dimensional lighting effect with parallax, depth and brightness variability or twinkling among different viewing angles using an LED substrate and different optic component layers including one or more obscuration patterns and a reflection chamber for unobscured light from LEDs components not obscured by the one or more obscuration patterns. The LED substrate can employ mini or micro scale package LEDs or their unpackaged LED dies for slim profile lighting assembly. The LED substrate and different optic component layers can be curved, employ direct illumination and occultation imaging.

Abstract: Glucose-sensing luminescent dyes of formula (IV-I), polymers, and sensors are provided. Additionally, systems including the sensors and methods of using these sensors and systems are provided.

Abstract: A portable cooler container with active temperature control includes a double-walled insulated container body with a chamber to receive and hold temperature sensitive products. A control system is at least partially disposed between an outer wall and an inner wall of the container body. An electronic display screen on one of the lid and the container body configured to display shipping address information for the portable cooler container.

Abstract: In the disclosed systems and methods for characterizing a cancer condition of a tissue in a subject, a computer system inputs information into an ensemble model. The information includes, for each respective class of radiomics features in a plurality of classes of radiomics features, a corresponding value for each respective radiomic feature in a corresponding plurality of radiomics features of the respective class of radiomics features obtained from a medical imaging dataset. The ensemble model comprises a plurality of component models. The computer system obtains as output from each respective component model in the plurality of component models a corresponding component prediction for the cancer condition, thereby obtaining a plurality of component predictions for the cancer condition. The computer system combines the plurality of component predictions to obtain as output of the ensemble model a characterization of the cancer condition.

Abstract: In the disclosed systems and methods for categorizing medical data, a computer system obtains, in electronic form, a plurality of medical records. Each medical record includes corresponding medical data from a respective medical evaluation and corresponding metadata comprising a plurality of attributes about the respective medical evaluation. Each respective attribute comprises a corresponding string of text. The computer system determines, for each respective pair of medical records consisting of a first medical record and a second medical record, a corresponding pairwise similarity between, for each respective attribute in a set of attributes, the corresponding string of text for the first medical record and the corresponding string of text for the second medical record. The computer system identifies a first subset of the plurality of medical records. Each respective medical record in the first subset is connected to each other through pairwise similarities that each satisfies a similarity threshold.

Abstract: A portable cooler container includes a container body with a payload chamber. The container body has an insulated vessel and a temperature control system that cools the payload chamber.

Abstract: A beverage dispensing machine (e.g., coffee maker) has a cooling unit. The cooling unit includes a thermal mass. The cooling unit is operable to reduce a temperature of at least a portion of the thermal mass. The cooling unit also includes a passageway within which a beverage flows, the passageway being in thermal communication with the thermal mass that cools the beverage as it flows within the passageway to chill the beverage before it is dispensed.

Abstract: A portable cooler container is provided, with a payload chamber for one or more temperature sensitive or perishable goods. A heating or cooling unit is disposed in the payload chamber. The cooling unit includes a body of heat regulating material (e.g., PCM) and electronics (e.g., a controller, memory, a GPS sensor, parameter sensor(s), visual indicators, power storage elements and/or a wireless communication system) to sense information of the payload, heating or cooling module or portable cooler container and transmit said information to a remote electronic device or cloud-based data storage system.

Abstract: Some embodiments described herein relate to a sensor that includes a first a first polymer-luminescent sensing compound configured to produce a first luminescent signal in the presence of a first analyte and a second polymer-luminescent sensing compound configured to produce a second luminescent signal in the presence of a second analyte. The second luminescent signal can have a luminescent lifetime that is at least 1.1 times greater than a luminescent lifetime of the first luminescent signal. Such temporally differences in signal can be used to deconvolute the first luminescent signal from the second luminescent signal even when, for example, the first luminescent signal and the second luminescent signal have the same or a similar emission spectrum.