Abstract: An absorption spectroscopy process uses a single radiation beam with two or more pulsed beams (including at least a signal beam and a reference beam) that are passed into a liquid sample to a variable effective depth and then reflected out of the liquid sample where it is detected and processed to obtain a value over a preselected time. As values are determined for multiple effective depths, a sampling dataset is obtained which is used to calculate a concentration level of a targeted particle in the liquid sample by use of calibration dataset obtained from use of known samples.

Abstract: Increased precision for liquid absorption spectroscopy, especially for in vivo samples of human analytes, is obtained by varying the signal or signal and interference central wavelengths when the temperature of the sample site varies beyond a selected threshold used for determining standardized signal or signal and interference central wavelengths. The amount of variance for a central wavelength of the signal beam which includes 1,150 nm is approximately 2 nm or less.

Abstract: A process quantifies a concentration of a targeted molecule in a liquid sample by pulsing signal and reference beams from their own sources, then spatially combining the pulsed beams into a single radiation beam which passes into the liquid sample and then detecting pulsed output beams after the single radiation beam passes out of the liquid sample. The pulsed outputs of the signal and reference beams are processed to obtain a value over a preselected period of time and, if an interference beam is used, it is processed with the reference beam to obtain a calibration curve adjustment representative of optical interference represented by at least one interfering molecule concentration which is used to calculate the concentration level of the targeted particle in the liquid sample. Two detectors, which may have an optical co-axial configuration, can be used for detection of pulsed beams.

Abstract: A process for quantifying a concentration of a targeted molecule in a liquid sample in which a signal beam and a reference beam (and also optionally an interference beam) are pulsed, each beam being pulsed from its own source (preferably at narrow bandwidths), the pulsed beams are spatially combined into a single radiation beam which passes into the liquid sample and then pulsed output beams are detected after the single radiation beam passes out of the liquid sample. The pulsed signal beam output and the pulsed reference beam are processed to obtain a value over a preselected period of time and, if an interference beam is used, it is processed with the reference beam to obtain a calibration curve adjustment representative of optical interference represented by at least one interfering molecule concentration which is used to calculate the concentration level of the targeted particle in the liquid sample.

Abstract: The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Abstract: A process and sensor system useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix wherein the sample volume is configured so that a sampling error caused by changes of the targeted molecule passing in and out of the sample volume is approximately the same or less than a measurement error caused by an accuracy limit of electronic components and optical elements used in the sensor system.

Abstract: A process and sensor system useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix wherein the sample volume is configured so that a sampling error caused by changes of the targeted molecule passing in and out of the sample volume is approximately the same or less than a measurement error caused by an accuracy limit of electronic components and optical elements used in the sensor system.

Abstract: The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Abstract: The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Abstract: The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Abstract: For determining concentration of targeted molecules MG in a liquid sample admixed with interfering molecules MJ which overlap their absorption band, a special NDIR sampling and calibration technique is employed. Besides the signal source, a reference and one or more interference sources are added. The selection of the wavelength for the interference sources enables its measured transmittance value to be used for deciding the validity of the calibration curve for molecules MG in the liquid sample. This value can further be used to adjust the calibration curve via a parameter linking the transmittances measured at the signal and interference wavelength channels in order to assure its validity.

Abstract: For determining concentration of targeted molecules MG in a liquid sample admixed with interfering molecules MJ which overlap their absorption band, a special NDIR sampling and calibration technique is employed. Besides the signal source, a reference and one or more interference sources are added. The selection of the wavelength for the interference sources enables its measured transmittance value to be used for deciding the validity of the calibration curve for molecules MG in the liquid sample. This value can further be used to adjust the calibration curve via a parameter linking the transmittances measured at the signal and interference wavelength channels in order to assure its validity.

Abstract: A glucose sensor measures glucose molecules in vivo through use of NDIR in which scattering noise is reduced and Absorption Interference Noise (AIN) is suppressed with a reflection technique. Electronics are used to provide an output of glucose concentration glucose in a liquid sampling matrix after it has been determined that a calibration curve is valid after signal processing is used to obtain average ratio values for reflected signal/reference channels and interference/reference channel obtained after a pulsed beam from signal, interference and reference sources is directed at an inclined angle to a normal of a spot of the liquid sampling matrix. The signal, interference and reference sources are each pulsed at a preselected frequency of at least N Hz which is sufficiently fast so that a given molecule of glucose or interfering molecule will not pass in and out of the liquid sampling matrix within the preselected frequency.

Abstract: A glucose sensor measures glucose molecules in vivo through use of NDIR in which scattering noise is reduced and Absorption Interference Noise (AIN) is suppressed with a reflection technique. Electronics are used to provide an output of glucose concentration glucose in a liquid sampling matrix after it has been determined that a calibration curve is valid after signal processing is used to obtain average ratio values for reflected signal/reference channels and interference/reference channel obtained after a pulsed beam from signal, interference and reference sources is directed at an inclined angle to a normal of a spot of the liquid sampling matrix. The signal, interference and reference sources are each pulsed at a preselected frequency of at least N Hz which is sufficiently fast so that a given molecule of glucose or interfering molecule will not pass in and out of the liquid sampling matrix within the preselected frequency.

Abstract: For determining concentration of a targeted molecule M in a liquid sample admixed with interfering molecules MJ which overlap its absorption band, a NDIR reflection sampling technique is used. Besides the signal source, a reference and an interference source are added. M is calculated by electronics which use Rave(t) from a pulsed signal and reference channel output and a calibration curve which is validated by use of RJava(t2) from a pulsed interference and reference channel output. Signal, interference and reference sources are pulsed at a frequency which is sufficiently fast so that a given molecule of M or MJ will not pass in and out of the liquid sampling matrix within the pulsing frequency.

Abstract: Two coherent narrow bandwidth infrared beams, the Signal and the Reference, are incident at an angle and at high frequency sequentially and alternately at the same spot of a whole blood/body tissues sample. The Signal beam has a center wavelength which falls within an absorption line of glucose in whole blood (e.g. 1.409?). The Reference beam has a center wavelength which does not coincide with any known absorption lines of glucose in whole blood (e.g. 1,278?). Radiation emitted from the spot at which the beams penetrate into the sample and subsequently emanate from it after multiple scattering and spurious absorption effects is collected by a lens onto an infrared detector. The ratio of the voltage detected from the emerging Signal beam over that of the Reference beam is processed to yield the value of glucose concentration in the whole blood/body tissue sample.

Abstract: NDIR is used to determine a concentration of a chosen molecule M in a liquid sample which contains one or more interfering molecules MJ which absorb radiation at the signal wavelength used in the NDIR process by addition of an interference source. M is calculated by electronics which use Rave(t) from a pulsed signal and reference channel output and a calibration curve which is validated by use of RJave(t2) from a pulsed interference and reference channel output. Signal, interference and reference sources are pulsed at a frequency which is sufficiently fast so that a given molecule of M or MJ will not pass in and out of the liquid sampling matrix within the pulsing frequency.

Abstract: A concentration of glucose in a blood sample is determined through use of a signal channel output/reference channel ratio obtained by use of an NDIR absorption technique in which scattering noise attributable to the liquid phase is reduced by alternately and successively pulsing infrared radiation from signal and reference sources which are multiplexed and collimated into a pulsed beam directed through the sample space containing the liquid phase and the pulse frequency is sufficiently fast so that a given molecule of glucose will not pass in and out of the sample space within the pulse frequency.

Abstract: A concentration of a chosen molecule in a liquid phase in a sample space is determined through use of a signal channel output/reference channel ratio obtained by use of an NDIR absorption technique in which scattering noise attributable to the liquid phase is reduced by alternately and successively pulsing infrared radiation from signal and reference sources which are multiplexed and collimated into a pulsed beam directed through the sample space containing the liquid phase and the pulse frequency is sufficiently fast so that a given molecule of the chosen molecule will not pass in and out of the sample space within the pulse frequency.

Abstract: A gas sample separated from transformer oil is circulated through an NDIR gas sensor system which obtains an acetylene concentration by calculating a detected acetylene concentration obtained by an absorption biased (“AB”) NDIR acetylene gas sensor, calculating a detected carbon dioxide concentration obtained by an AB NDIR carbon dioxide gas sensor, calculating a detected water vapor concentration obtained by an AB NDIR water vapor NDIR gas sensor and then determining the acetylene concentration from the detected acetylene concentration through use of the detected carbon dioxide and water vapor concentrations to compensate for their interference.