Patents by Inventor Jacob Yashphe

Jacob Yashphe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conversion of compactin to pravastatin by actinomadura
    Publication number: 20030199075
    Abstract: A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
    Type: Application
    Filed: May 12, 2003
    Publication date: October 23, 2003
    Inventors: Arnold L. Demain, Yulin Peng, Jacob Yashphe, Joseph Davis
  • Conversion of compactin to pravastatin by Actinomadura
    Patent number: 6566120
    Abstract: A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: May 20, 2003
    Assignee: Massachusetts Institute of Technology
    Inventors: Arnold L. Demain, Yulin Peng, Jacob Yashphe, Joseph Davis
  • Conversion of compactin to pravastatin by actinomadura
    Publication number: 20010026934
    Abstract: A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
    Type: Application
    Filed: April 13, 2001
    Publication date: October 4, 2001
    Inventors: Arnold Demain, Yulin Peng, Jacob Yashphe, Joseph Davis
  • Conversion of compactin to pravastatin by Actinomadura
    Patent number: 6274360
    Abstract: A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: August 14, 2001
    Assignee: Massachusetts Insitute of Technology
    Inventors: Arnold L. Demain, Yulin Peng, Jacob Yashphe, Joseph Davis
  • Conversion of compactin to pravastatin by actinomadura
    Patent number: 5942423
    Abstract: A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 24, 1999
    Assignee: Massachusetts Institute of Technology
    Inventors: Arnold L. Demain, Yulin Peng, Jacob Yashphe, Joseph Davis