Patents by Inventor Jacobus Antonius Joseph DEN HARTOG

Jacobus Antonius Joseph DEN HARTOG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of VAP-1
    Patent number: 11787791
    Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: October 17, 2023
    Assignee: ACUCELA INC.
    Inventors: Mark W. Orme, Edison S. Zuniga, Vladimir A. Kuksa, Russell Stuart Craft, Eduardo Moreno Saveedra, Johannes Wilhelm Georg Meissner, Jacobus Antonius Joseph den Hartog, Albert Cornelis Dros
  • INHIBITORS OF VAP-1
    Publication number: 20230295140
    Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.
    Type: Application
    Filed: May 24, 2023
    Publication date: September 21, 2023
    Inventors: Mark W. ORME, Edison S. ZUNIGA, Vladimir A. KUKSA, Russell Stuart CRAFT, Eduardo Moreno SAVEEDRA, Johannes Wilhelm Georg MEISSNER, Jacobus Antonius Joseph den HARTOG, Albert Cornelis DROS
  • NLRP3 INHIBITORS
    Publication number: 20220289692
    Abstract: The present invention relates to substituted5-membered nitrogen containing heteroaryl compounds, such as triazole esters, where the heteroaryl ring is further substituted via a linking group such as —NH— with a cyclic group which in turn is substituted at the a-position. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.
    Type: Application
    Filed: September 4, 2020
    Publication date: September 15, 2022
    Inventors: David MILLER, Angus MACLEOD, Jonathan SHANNON, Jokin CARRILLO ARREGUI, Diana CASTAGNA, Jimmy VAN WILTENBURG, Jacobus Antonius Joseph DEN HARTOG
  • INHIBITORS OF VAP-1
    Publication number: 20220024915
    Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 27, 2022
    Inventors: Mark W. ORME, Edison S. ZUNIGA, Vladimir A. KUKSA, Russell Stuart CRAFT, Eduardo Moreno SAVEEDRA, Johannes Wilhelm Georg MEISSNER, Jacobus Antonius Joseph den HARTOG, Albert Cornelis DROS
  • INHIBITORS OF VAP-1
    Publication number: 20210387975
    Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.
    Type: Application
    Filed: September 27, 2019
    Publication date: December 16, 2021
    Inventors: Mark W. ORME, Edison S. ZUNIGA, Vladimir A. KUKSA, Russell Stuart CRAFT, Eduardo Moreno SAVEEDRA, Johannes Wilhelm Georg MEISSNER, Jacobus Antonius Joseph den HARTOG, Albert Cornelis DROS
  • NOVEL COMPOUNDS
    Publication number: 20210261512
    Abstract: The present invention relates to substituted 5-membered nitrogen containing heteroaryl compounds, such as sulfonyl triazoles, where the heteroaryl ring is further substituted, optionally via a linking group such as —NH—, with a cyclic group which in turn is substituted at the ?-position. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 26, 2021
    Applicant: INFLAZOME LIMITED
    Inventors: David MILLER, Angus MACLEOD, Stephen THOM, Christopher G. MCPHERSON, Thomas ALANINE, Jokin CARRILLO ARREGUI, Claire-Lise CIANA, Jonathan SHANNON, Jimmy VAN WILTENBURG, Jacobus Antonius Joseph DEN HARTOG