Abstract: Methods for treating tissue are provided. In one embodiment, an adjunct material, when secured to tissue, can receive at least one physiological element released from the tissue during healing progression of the tissue, and can exhibit first and second stiffnesses in compression that are approximately constant during first and second time periods from contact with the tissue, with the second stiffness decreasing with time as a function of at least one of oxidation, enzyme-catalyzed hydrolysis, and change of pH resulting from interaction with the at least one physiological element. In another embodiment, the adjunct can receive a unit volume of fluid that causes first and second portions of the adjunct to expand according to first and second expansion behaviors that differ from one another to apply different pressures to the tissue.

Abstract: A stapling assembly includes a cartridge, an anvil, and an adjunct. The cartridge has rows of staples disposed therein for deployment into tissue. The cartridge includes a knife slot extending therethrough between the rows for receiving a knife to cut tissue. The anvil is positioned opposite the cartridge. The adjunct is releasably retained on the cartridge or the anvil. The adjunct can be delivered to tissue by deployment of the staples from the cartridge. The adjunct can have a first shape, and a first adjunct portion can exhibit first expansion behavior in response to receipt of a volume of fluid, and a second adjunct portion can exhibit second expansion behavior in response to receipt of the volume of fluid such that the adjunct adopts a second shape. The difference between the first and second expansion behavior applies different pressures to different portions of tissue having the adjunct stapled thereto.

Abstract: A stapling assembly includes a cartridge, an anvil, and an adjunct. The cartridge has rows of staples disposed therein for deployment into tissue. The cartridge includes a knife slot extending therethrough between the rows for receiving a knife to cut tissue. The anvil is positioned opposite the cartridge. The adjunct is releasably retained on the cartridge or the anvil. The adjunct can be delivered to tissue by deployment of the staples from the cartridge. The adjunct can have a first shape, and a first adjunct portion can exhibit first expansion behavior in response to receipt of a volume of fluid, and a second adjunct portion can exhibit second expansion behavior in response to receipt of the volume of fluid such that the adjunct adopts a second shape. The difference between the first and second expansion behavior applies different pressures to different portions of tissue having the adjunct stapled thereto.

Abstract: Methods for treating tissue are provided. In one embodiment, an adjunct material, when secured to tissue, can receive at least one physiological element released from the tissue during healing progression of the tissue, and can exhibit first and second stiffnesses in compression that are approximately constant during first and second time periods from contact with the tissue, with the second stiffness decreasing with time as a function of at least one of oxidation, enzyme-catalyzed hydrolysis, and change of pH resulting from interaction with the at least one physiological element. In another embodiment, the adjunct can receive a unit volume of fluid that causes first and second portions of the adjunct to expand according to first and second expansion behaviors that differ from one another to apply different pressures to the tissue.