Patents by Inventor Jacqueline C. Linnes
Jacqueline C. Linnes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230249175Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: ApplicationFiled: April 14, 2023Publication date: August 10, 2023Applicant: Purdue Research FoundationInventors: Jacqueline C. Linnes, Megan Zaiyi Chiu, Rui Shen
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Patent number: 11633152Abstract: This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.Type: GrantFiled: October 16, 2020Date of Patent: April 25, 2023Assignee: Purdue Research FoundationInventors: Jacqueline C Linnes, Benjamin David Walters, Orlando S Hoilett
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Patent number: 11628434Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: GrantFiled: August 13, 2021Date of Patent: April 18, 2023Assignee: Purdue Research FoundationInventors: Jacqueline C. Linnes, Megan Zaiyi Chiu, Rui Shen
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Patent number: 11529626Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: GrantFiled: April 19, 2021Date of Patent: December 20, 2022Assignee: Purdue Research FoundationInventors: Jacqueline C. Linnes, Megan Zaiyi Chiu, Rui Shen
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Publication number: 20220032286Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: ApplicationFiled: August 13, 2021Publication date: February 3, 2022Applicant: Purdue Research FoundationInventors: Jacqueline C. Linnes, Megan Zaiyi Chiu, Rui Shen
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Patent number: 11136620Abstract: The invention features a fully-integrated rapid molecular diagnostic device that is low-cost, easy to manufacture, and simple to use. The device can serve as a molecular diagnostic platform for any disease, requiring little or no preparation or customization and can be made from simple materials (e.g., paper and adhesive film), making it inexpensive, portable, and disposable. The invention also provides methods of using the device for detection of one or more targets in a sample.Type: GrantFiled: December 12, 2016Date of Patent: October 5, 2021Assignee: Trustees of Boston UniversityInventors: Catherine M. Klapperich, Natalia M. Rodriguez, Jacqueline C. Linnes
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Publication number: 20210251514Abstract: The present disclosure relates to a novel device for selective collection and condensation of an exhaled breath, and the method of using the novel device. The novel device is portable and capable of collecting and condensing reproducible volumes of exhaled breath under about 10 minutes by using a unique temperature-based algorithm.Type: ApplicationFiled: June 18, 2019Publication date: August 19, 2021Applicant: Purdue Research FoundationInventors: Jacqueline C. Linnes, Divya Tankasala, Shubhankar S. Takle, Orlando S. Hoilett, Gabriel P. Ng, Michael S. Smith
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Patent number: 11090649Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: GrantFiled: April 19, 2017Date of Patent: August 17, 2021Assignee: Purdue Research FoundationInventors: Jacqueline C Linnes, Megan Zaiyi Chiu, Rui Shen
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Publication number: 20210237054Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: ApplicationFiled: April 19, 2021Publication date: August 5, 2021Applicant: Purdue Research FoundationInventors: Jacqueline C. Linnes, Megan Zaiyi Chiu, Rui Shen
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Publication number: 20210161467Abstract: This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.Type: ApplicationFiled: October 16, 2020Publication date: June 3, 2021Applicant: Purdue Research FoundationInventors: Jacqueline C. Linnes, Benjamin David Walters, Orlando S. Hoilett
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Publication number: 20190126270Abstract: The present invention relates to a low-cost, thermally reversible valve for paper-fluidic diagnostic devices. In particular, this invention demonstrates a tunable valve mechanism fabricated by wax-ink printing and localized heating via thin-film resistors to sequentially release liquids through a cellulose or nitrocellulose membrane. The wax-ink valve can obstruct fluid flow for a sustained time and are thermally actuated to release a controlled amount of liquid past the valve. This integrated paper-fluidic diagnostic assay device requires minimal user involvement, can be easily manufactured and tuned to meet various fluid delivery timing and incubation needs.Type: ApplicationFiled: April 19, 2017Publication date: May 2, 2019Applicant: Purdue Research FoundationInventors: Jacqueline C Linnes, Megan Zaiyi Chiu, Rui J Shen
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Publication number: 20190062820Abstract: The invention features a fully-integrated rapid molecular diagnostic device that is low-cost, easy to manufacture, and simple to use. The device can serve as a molecular diagnostic platform for any disease, requiring little or no preparation or customization and can be made from simple materials (e.g., paper and adhesive film), making it inexpensive, portable, and disposable. The invention also provides methods of using the device for detection of one or more targets in a sample.Type: ApplicationFiled: December 12, 2016Publication date: February 28, 2019Inventors: Catherine M. KLAPPERICH, Natalia M. RODRIGUEZ, Jacqueline C. LINNES
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Publication number: 20180203007Abstract: This invention relates to an improved version of paper-based analytical device and method for chromatographic chemical or immunoassays. Particularly, this present invention discloses a device and a method for reducing smears and improving sharpness and intensity of test sample readout for a multi-step chemical assay or immunoassay by introducing two additional elements, a time-delay pad (2) and a mixer (1), to the conventional two-dimensional paper network device (2DPN).Type: ApplicationFiled: January 19, 2018Publication date: July 19, 2018Applicant: Purdue Research FoundationInventors: Jacqueline C. Linnes, Laura M. Jamicich, Elizabeth A. Phillips, Kristin M. Byers, Anna R. Bird
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Publication number: 20180133001Abstract: A system for solar disinfection of fluid. One most preferred version of the system includes: (a) A UVTC, made of a polyethylene laminate film with an approximately rectangular plan, providing: a. A first compartment, b. A second compartment for holding fluid, with a port to fill and dispense. (b) A Disinfection Monitor Module (“DMM”) located in the first compartment which: a. Includes at least one sensor to measure light (e.g. solar UV) intensity b. Provides at least one user interface including: c. Contains a wireless communication interface d. Operates according to a process that ensures sufficient cumulative exposure of the contained fluid to solar UV to achieve adequate solar disinfection. Alternative embodiments may also include sensors to detect additional characteristics, such as transmittance, turbidity, “combined transmittance,” and/or temperature.Type: ApplicationFiled: January 12, 2018Publication date: May 17, 2018Applicant: PotaVida, IncInventors: Charles B. Matlack, Tyler B. Davis, Jacqueline C. Linnes