Patents by Inventor Jacqueline Chu

Jacqueline Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108241
    Abstract: Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram).
    Type: Application
    Filed: December 15, 2023
    Publication date: April 4, 2024
    Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., The General Hospital Corporation
    Inventors: Robert S. Langer, Carlo Giovanni Traverso, Malvika Verma, Feyisope Eweje, Christoph Winfried Johannes Steiger, Junwei Li, Nhi Phan, Hen-Wei Huang, Jacqueline Chu, John Ashraf Fou Salama
  • Patent number: 11850034
    Abstract: Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram).
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: December 26, 2023
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Robert S. Langer, Carlo Giovanni Traverso, Malvika Verma, Feyisope Eweje, Christoph Winfried Johannes Steiger, Junwei Li, Nhi Phan, Hen-Wei Huang, Jacqueline Chu, John Ashraf Fou Salama
  • Publication number: 20230202507
    Abstract: Systems, methods, and computer-readable media are disclosed for a control system for an autonomous vehicle (AV) simulator. A disclosed method comprises receiving configuration information for simulating a virtual environment of a three-dimensional (3D) scene; generating a plurality of simulation configurations for simulating the virtual environment based on a parameter specified in the configuration information; for each simulation configuration of the plurality of simulation configurations, simulating the virtual environment within an AV simulator using a virtual sensor based on the simulation configuration; evaluating the simulations of the virtual environment using a machine learning (ML) model for navigating an autonomous vehicle; comparing data recorded during the evaluation of the simulations using the ML model to drive data recorded in a physical environment by a vehicle having a first sensor; and generating a report associated with the virtual sensor based on a comparison of the data.
    Type: Application
    Filed: December 22, 2021
    Publication date: June 29, 2023
    Inventor: Jacqueline Chu
  • Publication number: 20230195968
    Abstract: Systems, methods, and computer-readable media are disclosed for a quick evaluation system for three-dimensional (3D) assets used in simulations for an autonomous vehicle (AV). A disclosed method comprises receiving drive data recorded in a physical environment by a vehicle having a first sensor; simulating the first sensor associated with a virtual autonomous vehicle in a virtual environment of a 3D scene including an object that at least partially corresponds to the physical environment; evaluating simulated data based on the simulation of the first sensor using a machine learning (ML) model; comparing evaluation data recorded during the evaluation of the simulation of the first sensor using the ML model to the drive data recorded in the physical environment; and generating a report based on a comparison of the evaluation data to a portion of the drive data to determine metrics associated with the object in the virtual environment.
    Type: Application
    Filed: December 20, 2021
    Publication date: June 22, 2023
    Inventors: Jacqueline Chu, Richard Stenson, Benjamin Goldstein
  • Publication number: 20220317301
    Abstract: The subject disclosure relates to techniques for integrating synthetic plants into a virtual scene. A process of the disclosed technology can include receiving a digital asset comprising synthetic foliage, processing the digital asset to modify at least one parameter associated with the synthetic foliage to generate a modified digital asset, acquiring synthetic sensor data corresponding with the modified digital asset, and calculating a classification score for the modified digital asset based on the synthetic sensor data.
    Type: Application
    Filed: March 31, 2021
    Publication date: October 6, 2022
    Inventors: Richard Stenson, Jacqueline Chu, Leftheris Kaleas
  • Publication number: 20220318450
    Abstract: The subject disclosure relates to techniques for generating localized atmospheric phenomena in a simulated environment. A process of the disclosed technology can include generating a plurality of volumetric sequences, generating a corresponding plurality of sequence slices for each of the plurality of volumetric sequences, and compiling the plurality of volumetric sequences to generate a synthetic localized atmospheric event.
    Type: Application
    Filed: March 31, 2021
    Publication date: October 6, 2022
    Inventors: Richard Stenson, Jacqueline Chu, Leftheris Kaleas
  • Publication number: 20210353174
    Abstract: Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram).
    Type: Application
    Filed: May 12, 2021
    Publication date: November 18, 2021
    Applicants: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., The General Hospital Corporation
    Inventors: Robert S. Langer, Carlo Giovanni Traverso, Malvika Verma, Feyisope Eweje, Christoph Winfried Johannes Steiger, Junwei Li, Nhi Phan, Hen-Wei Huang, Jacqueline Chu, John Ashraf Fou Salama