Patents by Inventor Jacqueline Fournier

Jacqueline Fournier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 4-substituted tetrahydropyridines for the manufacture of medicaments acting upon TGF-? 1
    Patent number: 7320982
    Abstract: The invention relates to the use of a compound of formula (I): for the preparation of pharmaceutical compositions for increasing the circulating, cellular and extracellular levels of TGF-?1.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: January 22, 2008
    Assignee: sanofi-aventis
    Inventors: Françoise Bono-Combie, Jacqueline Fournier, Jean Marc Herbert, Isabelle Lamarche, Umberto Guzzi
  • Preparation of benzoylalkyl-1,2,3,6-tetrahydropyridines and use thereof
    Patent number: 7297799
    Abstract: The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: November 20, 2007
    Assignee: Sanofi-Aventis
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • PREPARATION OF BENZOYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES AND USE THEREOF
    Publication number: 20070054931
    Abstract: The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.
    Type: Application
    Filed: November 1, 2006
    Publication date: March 8, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
    Patent number: 7151107
    Abstract: The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: December 19, 2006
    Assignee: Sanofi-aventis
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
    Publication number: 20050222187
    Abstract: The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.
    Type: Application
    Filed: May 24, 2005
    Publication date: October 6, 2005
    Applicant: Sanofi-Aventis
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
    Patent number: 6936621
    Abstract: The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: August 30, 2005
    Assignee: Sanofi-Aventis
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of 4-substituted tetrahydropyridines for the manufacture of medicaments acting upon TGF-beta 1
    Publication number: 20040157868
    Abstract: The invention relates to the use of a compound of formula (I): 1
    Type: Application
    Filed: February 5, 2004
    Publication date: August 12, 2004
    Inventors: Francoise Bono-Combie, Jacqueline Fournier, Jean Marc Herbert, Isabelle Lamarche, Umberto Guzzi
  • Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
    Publication number: 20040122032
    Abstract: The invention relates to the use of compounds of formula 1
    Type: Application
    Filed: December 5, 2003
    Publication date: June 24, 2004
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of 4-substituted tetrahydropyridines for the manufacture of medicaments acting upon TGF-&bgr;1
    Patent number: 6693118
    Abstract: The invention relates to the use of a compound of formula (I): for the preparation of pharmaceutical compositions for increasing the circulating, cellular and extracellular levels of TGF-&bgr;1.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: February 17, 2004
    Assignee: Sanofi-Synthelabo
    Inventors: Françoise Bono-Combie, Jacqueline Fournier, Jean Marc Herbert, Isabelle Lamarche, Umberto Guzzi
  • Use of 4-substituted tetrahydropyridines for the manufacture of medicament s acting upon TGF-beta 1
    Publication number: 20020091143
    Abstract: The invention relates to the use of a compound of formula (I): 1
    Type: Application
    Filed: November 20, 2001
    Publication date: July 11, 2002
    Inventors: Francoise Bono-Combie, Jacqueline Fournier, Jean Marc Herbert, Isabelle Lamarche, Umberto Guzzi
  • Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
    Publication number: 20020058672
    Abstract: The invention relates to the use of compounds of formula 1
    Type: Application
    Filed: November 20, 2001
    Publication date: May 16, 2002
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of benzoylalkyl-1,2,3,6-tetrahydropyridines
    Patent number: 6358965
    Abstract: The invention relates to the use of compounds of formula for the preparation of medicines designed for the treatment of neuronal and cerebral disorders. The invention also relates to the compounds of formula: a process for their preparation and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: March 19, 2002
    Assignee: Sanofi-Synthelabo
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of 4-substituted tetrahydropyridines for making medicines acting on TGF-&bgr;1
    Patent number: 6342505
    Abstract: The invention relates to the use of a compound of formula (I): for the preparation of pharmaceutical compositions for increasing the circulating, cellular and extracellular levels of TGF-&bgr;1.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: January 29, 2002
    Assignee: Sanofi-Synthelabo
    Inventors: Françoise Bono-Combie, Jacqueline Fournier, Jean Marc Herbert, Isabelle Lamarche, Umberto Guzzi
  • Diphenylalkyl-tetrahydropyridines, process for their preparation, and pharmaceutical compositions containing them
    Patent number: 6124318
    Abstract: The invention relates to compounds of the formula ##STR1## in which: Y is --CH-- or --N--;R.sub.1 is a halogen or a CF.sub.3, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy group;R.sub.2 and R.sub.3 are each hydrogen or a (C.sub.1 -C.sub.3)alkyl;n is 0 or 1; andPh.sub.1 and Ph.sub.2 are each independently an unsubstituted, monosubstituted or polysubstituted phenyl group;to a process for their preparation and to the pharmaceutical compositions containing them.These compounds have neurotrophic and neuroprotective activity.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: September 26, 2000
    Assignee: Sanofi-Synthelabo
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi
  • Use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyr idine for preparing drugs for treating amyotrophic lateral sclerosis
    Patent number: 6043251
    Abstract: The present invention relates to the use of 1-(2-naphth-2-ylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid ine or its addition salts with pharmaceutically acceptable acids for the preparation of drugs intended for the treatment of amyotrophic lateral sclerosis (ALS).
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: March 28, 2000
    Assignee: Sanofi
    Inventors: Patrice Douillet, Jacqueline Fournier
  • 1-Phenylalkyl-1,2,3,6-tetrahydropyridines for treating Alzheimer's disease
    Patent number: 6034090
    Abstract: The invention relates to compounds of the formula in which: Y is --CH-- or --N--; R.sub.1 is hydrogen, a halogen or a CF.sub.3, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy group; R.sub.2 is a methyl or ethyl group; R.sub.3 and R.sub.4 are each hydrogen or a (C.sub.1 -C.sub.3)alkyl; and X is:(a) a (C.sub.1 -C.sub.6)alkyl, a (C.sub.1 -C.sub.6)alkoxy, a (C.sub.3 -C.sub.7)carboxyalkyl, a (C.sub.1 -C.sub.4)alkoxy-carbonyl(C.sub.1 -C.sub.6)alkyl, a (C.sub.3 -C.sub.7)carboxyalkoxy or a (C.sub.1 -C.sub.4)alkoxycarbonyl-(C.sub.1 -C.sub.6)alkoxy;(b) a radical selected from (C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkoxy, (C.sub.3 -C.sub.7)-cycloalkylmethyl, (C.sub.3 -C.sub.7)cycloalkylamino and cyclohexenyl, it being possible for said radical to be substituted by a halogen, hydroxyl, (C.sub.1 -C.sub.4)-alkoxy, carboxyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, amino or mono- or di-(C.sub.1 -C.sub.4)-alkylamino; or(c) a group selected from a phenyl, phenoxy, phenylamino, N-(C.sub.1 -C.sub.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: March 7, 2000
    Assignee: Sanofi-Synthlabo
    Inventors: Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi
  • 4-aryl-1-phenylalkyl-1,2,3,6-tetrahydropyridines having neurotrophic and neuroprotective activity
    Patent number: 5981754
    Abstract: The present invention relates to the compounds of formula (I) ##STR1## wherein Y is --CH-- or --N--; R.sub.1 is hydrogen, a halogen or a CF.sub.3, (C.sub.3 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy group; R.sub.2 is hydrogen, a halogen, a hydroxyl or a CF.sub.3, (C.sub.3 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy group; R.sub.3 and R.sub.4 are each hydrogen or a (C.sub.1 -C.sub.3)alkyl; and X is (a) a (C.sub.3 -C.sub.6)alkyl, a (C.sub.3 -C.sub.6)alkoxy, a (C.sub.3 -C.sub.7)carboxyalkyl, a (C.sub.1 -C.sub.4)-alkoxycarbonyl(C.sub.3 -C.sub.6)alkyl, a (C.sub.3 -C.sub.7)carboxyalkoxy or a (C.sub.1 -C.sub.4)alkoxycarbonyl(C.sub.3 -C.sub.6)alkoxy; (b) a radical selected from a (C.sub.3 -C.sub.7)cycloalkyl, (C.sub.3 -C.sub.7)cycloalkoxy, (C.sub.3 -C.sub.7)cycloalkylmethyl, (C.sub.3 -C.sub.7)cycloalkylamino and cyclohexenyl, it being possible for said radical to be substituted by a halogen, hydroxyl, (C.sub.1 -C.sub.4)alkoxy, carboxyl, (C.sub.1 -C.sub.4)alkoxycarbonyl, amino or mono- or di-(C.sub.1 -C.sub.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: November 9, 1999
    Assignee: Sanofi
    Inventors: Domenico Badone, Marco Baroni, Rosanna Cardamone, Jacqueline Fournier, Umberto Guzzi, Alessandra Ielmini
  • Use of a 1-(2-naphthylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridi ne for the manufacture of a medicament for the treatment of cerebral and neuronal diseases
    Patent number: 5468753
    Abstract: The invention concerns the use of i.a. 1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyri dine and its pharmaceutically acceptable addition salts for the preparation of medicaments suitable for the treatment and/or prophylaxis of neuronal degenerative processes including senile dementia, vascular dementia, and Alzheimer's disease.
    Type: Grant
    Filed: October 20, 1993
    Date of Patent: November 21, 1995
    Assignee: Sanofi
    Inventors: Francois X. Coude, Jacqueline Fournier, Umberto Guzzi
  • Use of a 1-(2-naphthylethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridi ne for the manufacture of a medicament for the treatment of cerebral and neuronal diseases
    Patent number: 5270320
    Abstract: The invention concerns the use of i.a. 1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyri dine and its pharmaceutically acceptable addition salts for the preparation of medicaments suitable for the treatment and/or prophylaxis of neuronal degenerative processes including senile dementia, vascular dementia, and Alzheimer's disease.
    Type: Grant
    Filed: November 7, 1991
    Date of Patent: December 14, 1993
    Assignee: Elf Sanofi
    Inventors: Francois X. Coude, Jacqueline Fournier, Umberto Guzzi
  • Method for evaluating neuronal activity of a drug
    Patent number: 5229389
    Abstract: The invention concerns the use of i.a. 1-[2-(2-naphthyl)-ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyr idine and its pharmaceutically acceptable addition salts for the preparation of medicaments suitable for the treatment and/or prophylaxis of neuronal degenerative processes including senile dementia, vascular dementia, and Alzheimer's disease.
    Type: Grant
    Filed: May 21, 1991
    Date of Patent: July 20, 1993
    Assignee: SANOFI
    Inventors: Francois X. Coude, Jacqueline Fournier, Umberto Guzzi