Patents by Inventor Jacqueline Harding

Jacqueline Harding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Controlled and tunable precipitation of biomimetic apatites via in situ mineralization of an organic polymeric matrix
    Patent number: 10806827
    Abstract: The present invention is directed to a method for the tunable precipitation of apatite induced by a chemical reaction within a polymeric hydrogel, and the product made thereof. The present invention includes a pH dependent pathway for the hydrolysis of DCPD precursor phase. In addition to pH the stoichiometry of the CaP reactants can contribute to the composition of the CaP phase incorporated into the PVA hydrogels. At elevated pH the direct conversion of DCPD to apatite is observed. However, decreasing the reaction pH to 7.4 to mimic physiological conditions results in the inclusion of OCP as a transition step.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: October 20, 2020
    Assignee: Colorado School of Mines
    Inventors: Melissa Krebs, Jacqueline Harding
  • CONTROLLED AND TUNABLE PRECIPITATION OF BIOMIETIC APATITES VIA IN SITU MINERALIZATION OF AN ORGANIC POLYMERIC MATRIX
    Publication number: 20160346429
    Abstract: The present invention is directed to a method for the tunable precipitation of apatite induced by a chemical reaction within a polymeric hydrogel, and the product made thereof. The present invention includes a pH dependent pathway for the hydrolysis of DCPD precursor phase. In addition to pH the stoichiometry of the CaP reactants can contribute to the composition of the CaP phase incorporated into the PVA hydrogels. At elevated pH the direct conversion of DCPD to apatite is observed. However, decreasing the reaction pH to 7.4 to mimic physiological conditions results in the inclusion of OCP as a transition step.
    Type: Application
    Filed: June 1, 2016
    Publication date: December 1, 2016
    Applicant: Colorado School of Mines
    Inventors: Melissa Krebs, Jacqueline Harding