Patents by Inventor Jacqueline Jozefonvicz

Jacqueline Jozefonvicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dextran derivatives endowed, particularly with anti-coagulant properties and anti-complementary properties, their preparation and their biological uses
    Patent number: 4740594
    Abstract: The dextran derivatives have a molecular weight higher than about 5000 daltons and comprise statistically at least about 35% of units substituted by radicals having a COO.sup.- function and at least 3% of units comprising a group of structure ##STR1## wherein R.sub.1 is a single bond; or a ##STR2## group, R.sub.2 is an anion of an inorganic or an organic salt and n is a number from 1 to 4.
    Type: Grant
    Filed: November 30, 1984
    Date of Patent: April 26, 1988
    Assignee: Choay S.A.
    Inventors: Monique Mauzac, Jacqueline Jozefonvicz, Marcel Jozefonvicz
  • Process for the separation of antifactor VIII:C antibodies, more particularly usable for the purification of the blood plasma of a type a hemophiliac
    Patent number: 4736019
    Abstract: The process for the separation of antiVIII:C antibodies present in a liquid consists of contacting said liquid with a solid support constituted by a polymer or a copolymer having in its chain substitutable groups, whereof at least part is substituted by groups having an affinity for antiVIII:C antibodies and a selectivity for antiVIII:C antibodies compared with other immunoglobulins and then separating the liquid from the support on which have been adsorbed the antiVIII:C antibodies.Preferably use is made of polystyrene, to which have been fixed groups --SO.sub.3 Na and --SO.sub.2 Glu, --SO.sub.2 Threo, --SO.sub.2 OHPro or SO.sub.2 Lys. These supports can be used for ex-vivo purification in the column of the blood plasma of a type A hemophiliac.
    Type: Grant
    Filed: May 21, 1986
    Date of Patent: April 5, 1988
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Noureddine Bellattar, Danielle Gulino, Jacqueline Jozefonvicz
  • Products based on polymers or copolymers substituted by groups having selective affinity towards products involved in blood plasma coagulation and process for preparing same
    Patent number: 4568725
    Abstract: Product constituted by a polymer or a copolymer having in its chain substitutable groups to which are statistically fixed X and Y groups, in which X represents SO.sub.3 --R.sup.1, with R.sup.1 being a hydrogen atom or a physiologically acceptable metal, wherein the Y groups have the formula --SO.sub.2 --R.sup.2, in which R.sup.2 represents a radical derived from arginine or an arginine derivative, bonded by its amino function --NH-- to the radical --SO.sub.2 --.The invention also relates to a process for preparing such a product and to a process of the separation and purification of thrombin.
    Type: Grant
    Filed: June 21, 1984
    Date of Patent: February 4, 1986
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Catherine Boisson, Danielle Gulino, Jacqueline Jozefonvicz, Marcel Jozefonvicz