Patents by Inventor Jacqueline M. Mason

Jacqueline M. Mason has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TARGETING PTEN MUTANT DISEASES AND COMPOSITIONS THEREFOR
    Publication number: 20150182504
    Abstract: Provided herein are methods and compositions for treating a patient with cancer wherein the cancer is characterized by a PTEN gene mutation and/or a PI3K gene mutation. In particular embodiments, the methods comprise administering to the patient a composition comprising a therapeutically effective amount of a PLK4 antagonist.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 2, 2015
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Guohua Pan, Jacqueline M. Mason, Xin Wei, Miklos Feher
  • Methods of targeting PTEN mutant diseases and compositions therefor
    Patent number: 8933070
    Abstract: Provided herein are methods, uses and compositions for treating a patient with cancer wherein the cancer is characterized by a PTEN gene mutation. In particular embodiments, the methods comprise administering to the patient a composition comprising a therapeutically effective amount of a PLK4 antagonist, and identifying a patient that is likely to be responsive to PLK4 antagonist therapy, if PTEN gene mutation is present.
    Type: Grant
    Filed: July 4, 2011
    Date of Patent: January 13, 2015
    Assignee: University Health Network
    Inventors: Guohua Pan, Jacqueline M. Mason, Xin Wei, Miklos Feher
  • METHODS OF TARGETING PTEN MUTANT DISEASES AND COMPOSITIONS THEREFOR
    Publication number: 20130123273
    Abstract: Provided herein are methods, uses and compositions for treating a patient with cancer wherein the cancer is characterized by a PTEN gene mutation. In particular embodiments, the methods comprise administering to the patient a composition comprising a therapeutically effective amount of a PLK4 antagonist, and identifying a patient that is likely to be responsive to PLK4 antagonist therapy, if PTEN gene mutation is present.
    Type: Application
    Filed: July 4, 2011
    Publication date: May 16, 2013
    Applicant: UNIVERSITY HEALTH NETWORK
    Inventors: Guohua Pan, Jacqueline M. Mason, Xin Wei, Miklos Feher