Patents by Inventor Jacqueline S. Sampson

Jacqueline S. Sampson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of Streptococcus pneumoniae and immunization against Streptococcus pneumoniae infection
    Patent number: 6869767
    Abstract: The present invention relates to oligonucleotide primers, and methods of diagnosis using the primers, wherein particular primer pairs prime the universal amplification of an amplicon for specific Streptococcus pneumoniae from all 90 known serotypes. The amplicon includes at least a portion of the psaA gene of Steptococcus pneumoniae. In the methods, amplification of a biological sample using the primer pairs of the invention provide an amplicon only if the sample contains a serotype of Streptococcus pneumoniae. The invention further relates to an isolated nucleic acid including a nucleic acid amplicon obtained using a pair of oligonucleotide primers of the invention. In still a further aspect, the invention discloses a polypeptide including an amino acid sequence encoded by a nucleic acid amplicon obtained using oligonucleotide primers.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: March 22, 2005
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Jacqueline S. Sampson, Katherine E. Morrison, Jennifer Crook Whitmon, Edwin Ades, George M. Carlone