Abstract: The invention is notably directed to an oscillating reaction device. The device basically includes a structured layer of a matrix material and structural elements. Cavities are defined (for example, as blind holes) in the structured layer to allow the cavities to be filled with an oscillating reaction liquid containing nonpolar molecules of a given molecular species, with a view to triggering an oscillating reaction. Centers of the cavities are arranged according to a 2D lattice, whereby pairs of nearest-neighbor cavities of said cavities are, each, separated by a portion of the matrix material. This portion of material is selectively permeable to said nonpolar molecules. This, in operation, yields an inhibitory chemical coupling of the filled cavities of said pairs of nearest-neighbor cavities, where the inhibitory chemical coupling is mediated by said nonpolar molecules. Also, the structural elements connect the cavities to yield a positive chemical coupling of the filled cavities.