Patents by Inventor Jacquelynn J. Cook

Jacquelynn J. Cook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Platelet aggregation inhibition using low molecular weight heparin in combination with a GP IIb/IIIa antagonist
    Patent number: 6136794
    Abstract: A method for inhibiting platelet aggregation in a mammal comprising administering to the mammal a safe and therapeutically effective amount of a GPIIb/IIIa receptor antagonist or a pharmaceutically acceptable salt thereof and a safe and therapeutically effective amount of low molecular weight heparin. A method for inhibiting platelet aggregation in a mammal comprising administering to the mammal a safe and therapeutically effective amount of (2-S-(n-butylsulfonylamino)-3[4-(piperidin-4-yl)butyloxyphenyl]-propionic acid or a pharmaceutically acceptable salt thereof and a safe and therapeutically effective amount of low molecular weight heparin.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: October 24, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Jacquelynn J. Cook, Robert J. Gould, Frederic L. Sax
  • Fibrinogen receptor antagonist prodrugs
    Patent number: 5981584
    Abstract: Fibrinogen receptor antagonist prodrugs having the structure, for example, of ##STR1## more particularly, ##STR2##
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: November 9, 1999
    Assignee: Merck & Co., Inc.
    Inventors: Melissa S. Egbertson, Steve D. Young, George D. Hartman, Jacquelynn J. Cook
  • Heparin neutralization with platelet factor 4
    Patent number: 5204321
    Abstract: Circulating heparin in a mammal may be neutralized without substantial depletion of platelets or leukocytes by administering to the mammal a heparin neutralizing amount of purified PF4 or rPF4 or a heparin neutralizing fragment thereof.
    Type: Grant
    Filed: June 23, 1992
    Date of Patent: April 20, 1993
    Assignee: Repligen Corporation
    Inventors: Jacquelynn J. Cook, Stefan Niewarowski, Theodore E. Maione