Patents by Inventor Jacques A. L. Simond

Jacques A. L. Simond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-alkoxy-2-(N-pyrrolidino)-N-pyrimidinyl- or -N-pyrazinolpropylamines useful for treatment of cardiovascular disorders
    Patent number: 4762834
    Abstract: The present invention relates to new compounds of the general formula: ##STR1## in which Ar represents thienyl, furyl, pyridyl or an optionally substituted phenyl group,R represents a linear or branched alkyl group with 1 to 7 carbon atoms, andeither X.sub.1 or X.sub.2 represents nitrogen, the other being carbon,and pharmaceutically acceptable acid addition salts thereof, having valuable cardiovascular properties.
    Type: Grant
    Filed: August 20, 1986
    Date of Patent: August 9, 1988
    Assignee: Riom Laboratoires C.E.R.M. "Rl-Cerm", S.A.
    Inventors: Michel Combourieu, Jacques A. L. Simond, Andre J. C. Monteil
  • Aminoethyl-pyridine and pyrazine derivatives
    Patent number: 4668679
    Abstract: The invention relates to compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, in which X represents either --CH.dbd. or --N.dbd., R.sub.1 represents an alkyl radical having 1 to 5 carbon atoms, R.sub.2 represents hydrogen and R.sub.3 is an alkyl radical having 1 to 5 carbon atoms, or R.sub.2 and R.sub.3, together with the nitrogen atom to which they are bonded, represent a heterocyclic radical, such as pyrrolidinyl, morpholino, 4-phenyl-piperazinyl, in which the phenyl radical can carry one or more substituents, such as a halogen atom, an alkyl or alkoxy radical having 1 to 5 carbon atoms or the trifluoromethyl radical, or represents 4-(2-pyrimidinyl)-piperazinyl, having anti-bronchoconstrictory properties.
    Type: Grant
    Filed: December 24, 1985
    Date of Patent: May 26, 1987
    Assignee: Riom Laboratories C.E.R.M.
    Inventors: Jacques A. L. Simond, Patrick Carlier, Andr/e/ J. Monteil
  • 3-Alkoxy-2-(N-pyrolidino)-N-pyridyl-N-furyl(or thienyl) methyl-pyropyl amines useful as calcium antagonists
    Patent number: 4555514
    Abstract: The present invention relates to new compounds of the general formula: ##STR1## in which X represents oxygen or sulphur and R represents a linear or branched alkyl group with 1 to 7 carbon atoms,and pharmaceutically acceptable acid addition salts thereof, having valuable cardiovascular properties.
    Type: Grant
    Filed: January 9, 1985
    Date of Patent: November 26, 1985
    Assignee: Riom Laboratoires C.E.R.M. "RL-CERM" S.A.
    Inventors: Michel Combourieu, Jacques A. L. Simond, Andre J. Monteil
  • Ethers of 1-(2-propynyloxy)-2-amino-3-propanol
    Patent number: 4430332
    Abstract: The invention is dealing with compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, in which R.sub.1 and R.sub.2 each represent a lower alkyl radical or a phenyl radical, or, together with the carbon atom to which they are bound, a cycloalkyl radical having at the most 7 carbon atoms; R.sub.3 represents hydrogen, a lower alkyl radical, or the phenyl radical; R.sub.4 and R.sub.5 each represent a lower alkyl radical, or, together with the nitrogen atom to which they are bound, a heterocyclic amino radical such as the pyrrolidinyl or morpholino radicals; and R.sub.6 represents a lower alkyl radical, a phenyl radical, a benzyl radical, or the 1-ethynyl-cyclohexyl radical, which compounds can be used in the treatment of angina pectoris.
    Type: Grant
    Filed: December 19, 1980
    Date of Patent: February 7, 1984
    Assignee: Centre Europeen de Recherches Mauvernay
    Inventors: Patrick Carlier, Andre J. C. Monteil, Jacques A. L. Simond