Patents by Inventor Jacques Armand Henri BOLLEKENS

Jacques Armand Henri BOLLEKENS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS AND USES THEREOF IN THE TREATMENT OF CHRONIC HEPATITIS B INFECTION
    Publication number: 20230332230
    Abstract: Single nucleotide polymorphisms (SNPs) that are indicative of relapse after a HBV direct-acting antiviral agent (DAA) treatment, such as a NUC treatment in a chronic hepatitis B (CHB) infected subject are described. Also described are methods of using the SNPs in predicting the relapse in the HBV DAA treatment of CHB infection.
    Type: Application
    Filed: February 5, 2021
    Publication date: October 19, 2023
    Inventors: Marianne Isabelle TUEFFERD, Marjolein CRABBE, Jacques Armand Henri BOLLEKENS, Jeroen Marcel Maria Roger AERSSENS, Alessandro DI CARA
  • BIOMARKERS AND USES THEREOF IN THE TREATMENT OF CHRONIC HBV INFECTION
    Publication number: 20220090217
    Abstract: Immunogenetic biomarkers of viral control of chronic hepatitis B (CHB) infection that are indicative of relapse after a viral suppression treatment, such as a NUC treatment, in CHB infected subject are described. Also described are methods and compositions of using the immunogenetic biomarkers in predicting the relapse in the viral suppression treatment of CHB infection.
    Type: Application
    Filed: September 1, 2021
    Publication date: March 24, 2022
    Inventors: Marianne Isabelle TUEFFERD, Marjolein CRABBE, Jacques Armand Henri BOLLEKENS, Jeroen Marcel Maria Roger AERSSENS, Alessandro DI CARA
  • PYRIMIDINE PRODRUGS FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES
    Publication number: 20210214317
    Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
    Type: Application
    Filed: March 25, 2021
    Publication date: July 15, 2021
    Inventors: Jérôme Émile Georges GUILLEMONT, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, David Craig MC GOWAN, Werner Constant Johan EMBRECHTS, Bart Henri Theresia STOOPS, Florence Marie HERSCHKE, Jacques Armand Henri BOLLEKENS, Laurent Jacques Emile CALMUS
  • Pyrimidine prodrugs for the treatment of viral infections and further diseases
    Patent number: 10968184
    Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: April 6, 2021
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Jérôme Émile Georges Guillemont, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, David Craig McGowan, Werner Constant Johan Embrechts, Bart Henri Theresia Stoops, Florence Marie Herschke, Jacques Armand Henri Bollekens, Laurent Jacques Emile Calmus
  • PYRIMIDINE PRODRUGS FOR THE TREATMENT OF VIRAL INFECTIONS AND FURTHER DISEASES
    Publication number: 20200031779
    Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
    Type: Application
    Filed: September 28, 2017
    Publication date: January 30, 2020
    Inventors: Jérôme Émile Georges GUILLEMONT, Tim Hugo Maria JONCKERS, Pierre Jean-Marie Bernard RABOISSON, David Craig MC GOWAN, Werner Constant Johan EMBRECHTS, Bart Henri Theresia STOOPS, Florence Marie HERSCHKE, Jacques Armand Henri BOLLEKENS, Laurent Jacques Emile CALMUS