Patents by Inventor Jacques Barhanin

Jacques Barhanin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC USE OF CALCIUM-ACTIVATED CHLORIDE CHANNEL PEPTIDE ACTIVATOR
    Publication number: 20230242610
    Abstract: The present disclosure relates to a calcium-activated chloride channel peptide activator and its therapeutic use.
    Type: Application
    Filed: July 9, 2021
    Publication date: August 3, 2023
    Inventors: Guillaume SANDOZ, Pablo AVALOS PRADO, Jacques BARHANIN
  • Method of screening for compounds that can be used for the treatment of respiratory conditions
    Patent number: 8119362
    Abstract: The present invention relates to the use of a screening method for identifying candidate molecules that can be used for the treatment of respiratory conditions in a mammal, wherein the screening method comprises a step which comprises determining whether the functional activity of a TASK-2 polypeptide in the presence of a test molecule is decreased or eliminated compared with the functional activity of the TASK-2 polypeptide in the absence of the test molecule, the test molecule being considered to be a candidate molecule when it decreases or eliminates the functional activity.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: February 21, 2012
    Assignees: Centre National de la Recherche Scientifique—Cnrs, Universite Paul Cezanne Marseille III
    Inventors: Jacques Barhanin, Christian Gestreau, Richard Warth, Dirk Heitzmann, Jörg Thomas
  • METHOD OF SCREENING FOR COMPOUNDS THAT CAN BE USED FOR THE TREATMENT OF RESPIRATORY CONDITIONS
    Publication number: 20110014642
    Abstract: The present invention relates to the use of a screening method for identifying candidate molecules that can be used for the treatment of respiratory conditions in a mammal, wherein said screening method comprises a step which comprises determining whether the functional activity of a TASK-2 polypeptide in the presence of a test molecule is decreased or eliminated compared with the functional activity of said TASK-2 polypeptide in the absence of said test molecule, the test molecule being considered to be a candidate molecule when it decreases or eliminates said functional activity.
    Type: Application
    Filed: October 3, 2008
    Publication date: January 20, 2011
    Inventors: Jacques Barhanin, Christian Gestreau, Richard Warth, Dirk Heitzmann, Jörg Thomas
  • Isolated TWIK-1 potassium channel proteins
    Patent number: 7067625
    Abstract: This invention relates to the cloning of a member of a new potassium channel named TWIK-1. More specifically, it relates to an isolated and purified nucleic acid molecule coding for a protein constituting a potassium channel exhibiting the proper-ties and structure of the TWIK-1 type channel, as well as the protein coded by this nucleic acid molecule. The invention also relates to the use of this nucleic acid molecule to transform cells, and the use of these cells expressing the potassium channels exhibiting the properties and structure of the TWIK-1 type channel for the screening of drugs.
    Type: Grant
    Filed: January 11, 2000
    Date of Patent: June 27, 2006
    Inventors: Florian Lesage, Eric Guillemare, Michel Fink, Fabrice Duprat, Michel Lazdunski, Georges Romey, Jacques Barhanin
  • Family of mammalian potassium channels, their cloning and their use especially for the screening of drugs
    Patent number: 6013470
    Abstract: The present invention relates to the cloning of a member of a new potassium channel named TWIK-1. More specifically, it relates to an isolated and purified nucleic acid molecule coding for a protein constituting a potassium channel exhibiting the properties and structure of the TWIK-1 type channel, as well as the protein coded by this nucleic acid molecule.The invention also relates to the use of this nucleic acid molecule to transform cells, and the use of these cells expressing the potassium channels exhibiting the properties and structure of the TWIK-1 type channel for the screening of drugs.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: January 11, 2000
    Assignee: Centre National de la Recherche Scientifique-CNRS
    Inventors: Florian Lesage, Eric Guillemare, Michel Fink, Fabrice Duprat, Michel Lazdunski, Georges Romey, Jacques Barhanin