Patents by Inventor Jacques Chammas
Jacques Chammas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11738288Abstract: The present invention provides an automated system and method to isolate nucleated blood cells from whole blood or bone marrow. A disc mounted to a centrifuge system with spinning rotor is used to manipulate cells by channeling fluids while subjected to high gravitational field. The disc embodies at least two axisymmetric processing stations connected by a circular channel. Each station contains multiple chambers connected by fluidic channels to controllably transfer fluids. First stage separation allows for the isolation of the buffy coat layer while the second stage separation utilizes gradient density fluids to isolate the targeted nucleated cells from the buffy coat layer in the spinning disc.Type: GrantFiled: June 29, 2020Date of Patent: August 29, 2023Inventor: Jacques Chammas
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Publication number: 20230211063Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: March 10, 2023Publication date: July 6, 2023Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 11633528Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: December 21, 2021Date of Patent: April 25, 2023Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20220111132Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: December 21, 2021Publication date: April 14, 2022Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 11241522Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: January 10, 2020Date of Patent: February 8, 2022Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20210402328Abstract: The present invention provides an automated system and method to isolate nucleated blood cells from whole blood or bone marrow. A disc mounted to a centrifuge system with spinning rotor is used to manipulate cells by channeling fluids while subjected to high gravitational field. The disc embodies at least two axisymmetric processing stations connected by a circular channel. Each station contains multiple chambers connected by fluidic channels to controllably transfer fluids. First stage separation allows for the isolation of the buffy coat layer while the second stage separation utilizes gradient density fluids to isolate the targeted nucleated cells from the buffy coat layer in the spinning disc.Type: ApplicationFiled: June 29, 2020Publication date: December 30, 2021Inventor: Jacques Chammas
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Publication number: 20200147288Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: January 10, 2020Publication date: May 14, 2020Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10569004Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: June 12, 2019Date of Patent: February 25, 2020Assignee: DELCATH SYSTEMS, INC.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20190290823Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: June 12, 2019Publication date: September 26, 2019Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10369264Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: September 10, 2018Date of Patent: August 6, 2019Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20190001044Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: September 10, 2018Publication date: January 3, 2019Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10098997Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: July 17, 2017Date of Patent: October 16, 2018Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20180028740Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: July 17, 2017Publication date: February 1, 2018Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 9707331Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: November 7, 2012Date of Patent: July 18, 2017Assignee: DELCATH SYSTEMS, INC.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 8876683Abstract: A blood processing centrifuge comprising: a rotor having an axis of rotation and being controllably spun around the axis, a mechanism for processing whole blood within the rotor while spinning, a computer controlling blood processing operations, the computer being mounted to the rotor and spinning therewith.Type: GrantFiled: June 16, 2008Date of Patent: November 4, 2014Inventor: Jacques Chammas
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Publication number: 20140323284Abstract: A system for centrifugation and processing multi-units of blood simultaneously. The system having a plurality of equally spaced blood processing stations integrated to the rotor and spinning therewith around the axis of rotation. Each station is fit to receive a set of fluidly interconnected containers having blood for processing. Hydraulic means are used to automatically balance the rotor by having a mechanism to transfer fluid to special chambers on the processing stations in order to compensate for the weight variations of the multiple blood units mounted to the rotor. A Computer controls the centrifuge operations.Type: ApplicationFiled: May 6, 2014Publication date: October 30, 2014Inventor: Jacques Chammas
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Publication number: 20140158604Abstract: Compositions, methods, devices and media are provided for platelet storage container that prevents bacterial growth in the stored platelets. The invention relates to blood bank needs in safely storing platelets collected from donors for more than 5 days at room temperature. The container is built with natural adsorbent media that have the characteristics in capturing and killing bacteria and viruses. The stored platelets are isolated from the natural adsorbent material during storage to preserve their medical quality and safety.Type: ApplicationFiled: December 12, 2013Publication date: June 12, 2014Inventor: Jacques Chammas
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Publication number: 20110237418Abstract: A centrifuge system designed to receive a rotor having variable volumes adapted for collecting and centrifuging biological fluids. The centrifuge system encompasses a chuck that slides along the axis of rotation inside a rotating bucket. Thereby stretching or contracting the volume of the rotor.Type: ApplicationFiled: June 1, 2011Publication date: September 29, 2011Inventor: Jacques Chammas
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Patent number: 7998052Abstract: A rotor having variable volumes adapted for collecting and centrifuging biological fluids including an impermeable flexible body having a cylindrical shape with stretchable vertical walls and semi pliant base and a rigid circular member seamlessly joined to the top of the flexible body.Type: GrantFiled: March 7, 2006Date of Patent: August 16, 2011Inventor: Jacques Chammas
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Patent number: RE45315Abstract: A whole blood collection system includes an automated pump/control unit and an accompanying disposable blood set. When combined and connected to a source of anticoagulant, these elements allow automatic priming of the blood set with anticoagulant and automatic collection of anticoagulated blood product according to three different collection modes. The unit's pump and the blood set are specially designed to cooperate during the collection process to assure that the collected product has a precise blood to anticoagulant ratio. During the collection procedure, the pump/control unit automatically collects data relating to the procedure. Additional data specifically identifying components of the blood set, such as the blood collection bag, along with identification data on the donor's registration form may be scanned into the pump/controller unit by a scanner associated with the unit; this facilitates positive sample identification and tracking.Type: GrantFiled: June 10, 2004Date of Patent: December 30, 2014Assignee: Haemonetics CorporationInventors: Ronald O. Gilcher, Jacques Chammas, Joseph M. Medberry, Gary R. Stacey