Patents by Inventor Jacques Dachaud
Jacques Dachaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200024569Abstract: A device and method preparing a sample that may contain a target microorganism, includes: placing the sample in a container including: a device for the capture and/or concentration of a target microorganism or of a protein therefrom, including a capture and/or concentration support; a receptacle including; inlet and fluid guides, a device controlling the sample volume transferred from the fluid guide to the capture and/or concentration device through the inlet orifice, an outlet orifice; the capture/concentration device being attached to a wall of the receptacle; generating a displacement of all or part of the sample to the fluid guide and a defined sample volume from the fluid guide to the capture and/or concentration device, capturing and/or concentrating, on the capture and/or concentration support, the target microorganism or a protein from the microorganism, the volume of sample crossing the capture and/or concentration support then exiting again through the outlet orifice.Type: ApplicationFiled: October 9, 2017Publication date: January 23, 2020Applicant: BIOMÉRIEUXInventors: Fabien DACHAUD, Jacques DACHAUD, Frédéric FOUCAULT, Edgar MINASSIAN, David MOSTICONE, Jean-Claude RAYMOND
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Patent number: 9738864Abstract: A device (10) for detecting the presence of at least one microorganism in the contents (101, 201) of a container (100, 200) comprising a wall with a translucent zone, said detection device (10) comprising: a) at least one light source (11), such as a light-emitting diode (LED), capable of illuminating the contents of the container (100, 200) by emitting an excitation light beam through the translucent zone of the container (100, 200); b) at least one detection means (12, 13, 14, 15), such as a photodiode, for detecting at least one reaction light beam emitted in response to the illumination of the contents (101, 201) of the container (100, 200); said at least one light source (11) and said at least one detection means (12, 13, 14, 15) being equipped with at least one connection means (105, 205), to connect said at least one light source (11) and said at least one detection means (12, 13, 14, 15) to the wall of the container (100, 200), in the translucent zone, said at least one detection means (12, 13, 14Type: GrantFiled: June 10, 2014Date of Patent: August 22, 2017Assignee: BiomerieuxInventors: Bruno Colin, Corinne De La Foata, Jacques Dachaud, Fabienne Made
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Patent number: 9562260Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: GrantFiled: September 24, 2010Date of Patent: February 7, 2017Assignee: BIOMERIEUX, INC.Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catazariti, Louis Graziano, Bruno Colin, Cecile Paris, Jacque Dachaud
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Publication number: 20160152940Abstract: A device (10) for detecting the presence of at least one microorganism in the contents (101, 201) of a container (100, 200) comprising a wall with a translucent zone, said detection device (10) comprising: a) at least one light source (11), such as a light-emitting diode (LED), capable of illuminating the contents of the container (100, 200) by emitting an excitation light beam through the translucent zone of the container (100, 200); b) at least one detection means (12, 13, 14, 15), such as a photodiode, for detecting at least one reaction light beam emitted in response to the illumination of the contents (101, 201) of the container (100, 200); said at least one light source (11) and said at least one detection means (12, 13, 14, 15) being equipped with at least one connection means (105, 205), to connect said at least one light source (11) and said at least one detection means (12, 13, 14, 15) to the wall of the container (100, 200), in the translucent zone, said at least one detection means (12, 13,Type: ApplicationFiled: June 10, 2014Publication date: June 2, 2016Inventors: Bruno COLIN, Corinne DE LA FOATA, Jacques DACHAUD, Fabienne MADE
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Publication number: 20110020921Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: ApplicationFiled: September 24, 2010Publication date: January 27, 2011Applicant: bioMerieux, Inc.Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catanzariti, Louis Graziano, Bruno Colin, Cecile Paris, Jacques Dachaud
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Patent number: 7807449Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: GrantFiled: May 22, 2006Date of Patent: October 5, 2010Assignee: bioMerieux, Inc.Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catazariti, Louis Graziano, Bruno Colin, Cecile Paris, Jacque Dachaud
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Patent number: 7491497Abstract: A device for implementing a test card inside which sequential reactions and fluid transfer operations are performed under the effect of a control integrated into the card; the card includes at least two sequential reaction systems arranged in parallel, each reaction system having at least two fluid transfer systems arranged in series. A test card and the method for implementing the device and the card are also disclosed. The device contains at least one actuator per reaction line, and all the actuators are at a regular distance from one another, with the actuators preferably being equidistant. The invention is particularly applicable for the micromanipulation of fluids in biological applications.Type: GrantFiled: October 18, 2005Date of Patent: February 17, 2009Assignee: Biomerieux S.A.Inventors: Bruno Colin, Jacques Dachaud, Marie Privat, Cécile Paris
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Patent number: 7214529Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: GrantFiled: July 12, 2005Date of Patent: May 8, 2007Assignee: bioMérieux, Inc.Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catanzariti, Louis Graziano, Bruno Colin, Cecile Jaravel, Jacques Dachaud
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Publication number: 20060078466Abstract: The invention concerns a device for implementing a test card inside which sequential reactions and fluid transfer operations are performed under the effect of a control means integrated into the card; said card includes at least two sequential reaction systems arranged in parallel, each reaction system consisting of at least two fluid transfer systems arranged in series. The invention also concerns a test card and the method for implementing the device and the card. The device is characterized in that it contains at least one actuator per reaction line, and all the actuators are at a regular distance from one another, with the actuators preferably being equidistant. The invention is particularly applicable for the micromanipulation of fluids in biological applications.Type: ApplicationFiled: October 18, 2005Publication date: April 13, 2006Inventors: Bruno Colin, Jacques Dachaud, Marie Privat, Cecile Paris
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Publication number: 20050244887Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: ApplicationFiled: July 12, 2005Publication date: November 3, 2005Applicant: bioMerieux, Inc.Inventors: Bryan Kluttz, Geoff McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catanzariti, Louis Graziano, Bruno Colin, Cecile Jaravel, Jacques Dachaud
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Patent number: 6949376Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: GrantFiled: May 7, 2002Date of Patent: September 27, 2005Assignee: bioMerieux, Inc.Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catanzariti, Louis Graziano, Bruno Colin, Cecile Jaravel, Jacques Dachaud
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Patent number: 6929239Abstract: The invention concerns a device for performing a reaction or at least two reactions in parallel or in series, and for transferring a fluid flow, consisting of. an upper surface (2) and a lower surface (3) mutually linked by an edge (4); at least a duct (5) wherein a fluid flow (F1) can be generated by means transferring at least one sample (6) to be treated and/or analysed, and at least a valve (8) incorporated in each duct (4) for directing each sample (6) thereby controlling the transfers, reactions and analyses in the device. Each valve (8) consists of two means (9 and 10) integral with the device, the first means (9) being mobile between an inoperative position wherein the fluid transfer (6) is possible and an active position wherein said transfer cannot take place, and the second means (10) being mobile between a position wherein it is not in contact with said first means (9) and an active position wherein it deforms the first means (9) and it is activated by an actuator external to the device.Type: GrantFiled: September 8, 1999Date of Patent: August 16, 2005Assignee: Bio MerieuxInventors: Bruno Colin, Cécile Paris, Jacques Dachaud, Pierre Imbaud
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Patent number: 6902706Abstract: A valve (2), crossed by at least one channel (3), allowing to direct at least one fluid (F5) displaced by a transfer device within a test sample card (1), the card (1) featuring two faces (4 and 5) connected to one another (4) (5) by an edge (6). A card equipped with a device allowing several cards equipped with such valves to be implemented is made up of a flexible film (7), and/or which can be distorted, part of which is fixed to at least one of the faces (4 and/or 5) of said card (1) on the one hand, and a film compression device (7), which can be deactivated on the other hand. In addition, securing is carried out on at least one of the plane faces (4 and/or 5), for example, by a securing device located at the level of a recession (9) peripheral to the valve (2), such as a groove (9). The valve is particularly applicable in the field of diagnosis.Type: GrantFiled: June 21, 2000Date of Patent: June 7, 2005Assignee: Biomerieux S.A.Inventors: Bruno Colin, Jacques Dachaud
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Publication number: 20020127708Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: ApplicationFiled: May 7, 2002Publication date: September 12, 2002Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catanzariti, Louis Graziano, Bruno Colin, Cecile Paris, Jacques Dachaud
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Patent number: 6429007Abstract: An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature.Type: GrantFiled: October 18, 1999Date of Patent: August 6, 2002Assignee: bioMérieux, Inc.Inventors: Bryan W. Kluttz, Geoff A. McKinley, Fabio Gennari, Michel Guy, Christopher Cotter, Luigi Catanzariti, Louis Graziano, Bruno Colin, Cecile Jaravel, Jacques Dachaud